Gastro Intestinal Bleeding Clinical Trial
Official title:
Detection of Gastrointestinal Bleeding in Intensive Care Patients Via Biosensor Watch
The purpose of this study to improve methods of monitoring and diagnosing gastrointestinal bleeding via the E4 wristband, a biosensor watch.
The annual occurrence of gastrointestinal (GI) bleeding is approximately 150 per 100,000 in the US and accounts for 300,000 hospitalizations per year with a death rate of 5%. Qualitative assessments of blood tests monitoring patients with or are thought to have GI bleeding can lack accuracy and objectivity, delaying conformation of the bleed through endoscopy. Early endoscopies have been linked to more favorable outcomes for patients with heavier GI bleeding and earlier discharge times for patients with less severe GI bleeding. Additionally, laboratory values are not documented at regular intervals, which makes identifying when GI bleeding exactly occurred difficult. In this study, the investigators aim to improve methods of monitoring and diagnosing GI bleeding via the E4 wristband, a biosensor watch. Using data from the E4 wristband, the investigators will train a model to recognize GI bleeding through analyzing the heart rate and skin conductance of both patients with GI bleeding and who may have GI bleeding while they are not bleeding and while they are bleeding. Monitoring both types of patients while they are and are not bleeding will help the model discern which vital signs are critical. Additionally, the investigators will be using blood tests and other traditional methods of diagnosis to create a standard for vitals that characterize GI bleeding. If the E4 wristband is successfully able to accurately identify when a patient is experiencing GI bleeding, then speed of GI bleeding detection and the ability to monitor GI bleeding will dramatically increase, leading to quicker discharge times, reduced risk of rebleeding, and a lower death rate for afflicted patients. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05688501 -
Clinical-biological Score for Upper Gastrointestinal Bleeding
|
||
| Completed |
NCT03379285 -
Management of Digestive Haemorrhaging In CHRU of Brest During 2009 and 2014
|
N/A | |
| Recruiting |
NCT06096948 -
Nexpowder to Prevent Delayed Bleeding After Endoscopic Resection
|
N/A | |
| Active, not recruiting |
NCT05608577 -
RE-BLEED: A Digital Platform for Identifying Bleeding Patients - a Feasibility Study
|
||
| Recruiting |
NCT04788121 -
Efficacy of Tranexamic Acid in Upper Gastrointestinal Bleeding
|
Phase 3 | |
| Completed |
NCT03143569 -
Ventricular Assist Device Anti-Factor Xa (VAD ANTIX) Monitoring Study: a Prospective Randomized Feasibility Trial
|
N/A | |
| Recruiting |
NCT03090945 -
Pediatric Acute Gastrointestinal Bleeding Registry
|
||
| Recruiting |
NCT04979273 -
The Role of Hypertonic Dextrose Spray as Endoscopic Topical Hemostatic Agent for Acute Non-Variceal Upper GI Bleeding
|
N/A | |
| Not yet recruiting |
NCT06393868 -
Reducing Gastrointestinal Bleeding With Proton Pump Inhibitor Therapy in Acute Venous Thromboembolism
|
Phase 3 | |
| Completed |
NCT06345456 -
The Value of End-tidal Capnography in Gastrointestinal Bleeding
|
N/A | |
| Recruiting |
NCT03840057 -
Metoclopramide, Azithromycin, or Nondrug Pretreatment for UGIB to Reduce Second Endoscopy
|
Phase 2 | |
| Completed |
NCT05506150 -
Patient Important Gastrointestinal Bleeding in the ICU
|
||
| Active, not recruiting |
NCT05933135 -
Factor XIII Activity in Gastrointestinal Bleedings
|
||
| Completed |
NCT03955055 -
Study of Early Endocapsule (EC) in Clinical Decision Unit Versus Standard of Care Work-up for GI Bleeding
|
N/A | |
| Completed |
NCT04721964 -
Evaluation of the Effects of Routine Iron Supplementation in Children on Gastrointestinal Iron Losses
|
N/A | |
| Recruiting |
NCT03098537 -
Effects of Enteral Nutrition on Stress Ulcer Hemorrage. Multicenter Randomized Controlled Trial
|
N/A |