Gastric Tumor Clinical Trial
— GCQOL02Official title:
A Pilot Randomized Controlled Trial Examining the Differences of Quality of Life of Roux-En-Y Pouch Reconstruction and Conventional Roux-En-Y Reconstruction in Patients Undergoing Total Gastrectomy.
The purpose of this study is to find out more about differences of the quality of life in patients undergoing Roux-En-Y pouch reconstruction and conventional Roux-En-Y reconstruction. To find a better reconstruction for patients who received total gastrectomy.
Status | Recruiting |
Enrollment | 140 |
Est. completion date | May 2017 |
Est. primary completion date | May 2015 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 20 Years to 75 Years |
Eligibility |
Inclusion Criteria: - • Pathologically confirmed gastric malignant tumor at fUSCC (biopsy may be performed at other institutions but slides must be confirmed at SHCA, as is routine care at our institution) , and the patients be assessed must be carried out total gastrectomy by three specialists. - Patients 20-75 years old - Normal organ function, able to tolerate surgery, no clear contraindication for surgery - No evidence of metastases of adjacent organs - be able to provide follow-up over 2 years - No specific treatment for gastric cancer before surgery - In line with the Declaration of Helsinki and the requirements of the hospital ethics committee. - The subjects were able to understand and comply with the trial protocol, and signed informed consent. Exclusion Criteria: - • Synchronous or metachronous (less than five years) and with other malignancies. - Cirrhosis and portal hypertension - Associated with blood diseases - Serious heart/ lung and kidney dysfunction or with metabolic diseases such as diabetes, hyperthyroidism. - Suffering from a serious neurological diseases or psychological diseases affecting the life |
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
China | Fudan University Shanghai Cancer Center | Shanghai | Shanghai |
Lead Sponsor | Collaborator |
---|---|
Fudan University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in QOL (Quality of Life) | From preoperative following total gastrectomy, as measured with the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-C30 and QLQ-STO22 questionnaires | 5years | No |
Secondary | Nutritional status of patients | 5 years | No |
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