Clinical Trials Logo

Clinical Trial Summary

Confocal endomicroscopy (CLE) allows real-time in-vivo high-resolution and high-magnification imaging of the gastrointestinal epithelium, which is comparable to histopathology. Previous studies have investigated the accuracy of pCLE for diagnosis and differentiated of colorectal polyps, Barrett's esophagus and pancreaticobiliary strictures. However, to date there are limited data exploring the application of pCLE to gastric lesions, and this is the first study comparing the diagnosis of conventional forceps biopsy with that of pCLE using the final specimens obtained from endoscopic resection as a reference standard. The aims of this study were (1) the accuracy of pCLE compared to conventional forceps biopsy using histopathology results following endoscopic resection as a reference, and (2) comparison of "real time" in-vivo pCLE diagnosis with that of blinded "off-line" pCLE diagnosis, and off-line interobserver agreement.


Clinical Trial Description

n/a


Study Design

Observational Model: Cohort, Time Perspective: Prospective


Related Conditions & MeSH terms


NCT number NCT01688687
Study type Observational
Source Soonchunhyang University Hospital
Contact
Status Completed
Phase N/A
Start date February 2012

See also
  Status Clinical Trial Phase
Terminated NCT04977401 - EndoscoPic Submucosal dIssection Using geL Versus glycerOl for Submucosal iNjection N/A
Not yet recruiting NCT04083573 - Comparison of Diagnostic Performance of Medical Monitor and Medical Augmented Reality Glasses in Endoscopy: Observation Study
Completed NCT02504164 - Effect of Midazolam Premedication on the Satisfaction Levels of Patients After Endoscopic Submucosal Dissection N/A
Recruiting NCT01774266 - Detection of Methylated Reprimo in Plasma for Asymptomatic Gastric Cancer N/A
Completed NCT01921283 - Monitored Anesthesia Care With Propofol Plus Remifentanil During Endoscopic Submucosal Dissection: Evaluation of Bispectral Index Monitoring N/A
Completed NCT01435525 - Nexium Capsules Helicobacter Pylori Specific Clinical Experience Investigation N/A
Completed NCT01364324 - Pharmacokinetics of Anti-tuberculosis Drugs in Gastrectomized Patients
Recruiting NCT03837301 - Non-exposure Simple Suturing EFTR (NESS-EFTR) With Laparoscopic Sentinel Lymph Node Navigation for EGC (Senorita3-phase 2) Phase 2
Recruiting NCT05269056 - Early Detection of Gastric Cancer Using Plasma Cell-free DNA Fragmentomics
Not yet recruiting NCT03632746 - Verifying the Specificity of a New Method in Predicting Lymph Node Metastasis in Early Gastric Cancer Patients
Completed NCT01938326 - Pure Single Incision Laparoscopic Distal Gastrectomy (SIDG) Versus Totally Laparoscopic Distal Gastrectomy (TLDG) N/A
Recruiting NCT04602689 - Fibrin Glue After ESD for High Risk Patients of Bleeding N/A
Recruiting NCT05291728 - Screening for Early Gastric Cancer in Shaanxi Province
Not yet recruiting NCT06152783 - Confocal Laser Microendoscopy (CellTouch) for the Diagnosis of Early Gastric Cancer: A Multicenter Clinical Study
Completed NCT02189226 - Usefulness of Probe-based Confocal Laser Endo-microscopy in Delineation of Margin of Early Gastric Cancer for Endoscopic Submucosal Dissection N/A
Completed NCT04602299 - Setting the Shortest Examination Time of Gastroscopy to Improve the Detection Rate of Upper Gastrointestinal Tumors N/A
Completed NCT02562976 - OLGA Stage is More Appropriate in Predicting Early Gastric Cancer N/A
Recruiting NCT01132469 - Efficacy and Safety Study of Endoscopic Submucosal Dissection for Early Gastric Cancer N/A
Completed NCT03136354 - Prospective Randomized Trial Comparing Endoscopic Submucosal Dissection Against Laparoscopic Assisted Gastrectomy for Treatment of Early Gastric Cancer N/A
Completed NCT02216110 - Endoscopic Submucosal Dissection Versus Gastrectomy N/A