Clinical Trials Logo

Clinical Trial Summary

This is a randomized controlled trial to comparing the different simethicone administration strategies for esophagogastroscopy. Recent studies have indicated that the administration of simethicone before endoscopic examination could shorten the procedure time and improve the diagnostic rate of the gastric mucosal lesions. But the time interval between simethicone administration and the examination has not been fully determined. This study will test whether the time of taking simethicone before endoscopy could influence the performance of the procedure in a randomized controlled trial. The results may benefit the current clinical practice.


Clinical Trial Description

Esophagogastroscopy can enable the direct examination of the esophageal and gastric mucosal lesions, which has been widely applied in clinical practice. However, during the examination, too much water, foam or residues in the stomach will not only increase the procedure time and the misdiagnosis rate, but also decrease the patients' tolerance, for more efforts should be made to deal with the excessive water, foam or residues in order to obtain a clear view of the mucosa. Simethicone is also called poly-dimethylsiloxane, which can be used to remove the foam and water. Although simethicone has been routinely administrated before the esophagogastroscopy, the optimal strategy of administrating simethicone has not been clearly investigated, especially the time to administrate simethicone. Intaking simethicone too early will result in too excessive water in the stomach, while if the patients take it too late it doesn't take effects. Thus, this is a study to determine whether selecting different simethicone administration strategies could improve the performance of the esophagogastroscopy and minimize the patients' dissatisfaction. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03776916
Study type Interventional
Source Affiliated Hospital to Academy of Military Medical Sciences
Contact
Status Completed
Phase N/A
Start date May 1, 2019
Completion date August 31, 2019

See also
  Status Clinical Trial Phase
Completed NCT02105506 - Safety and Feasibility of TachoSil®: Application on Esophageal Anastomoses N/A
Completed NCT03198871 - IV Acetaminophen for Post-Operative Pain Management in Enhanced Recovery After Surgery (ERAS) Population Phase 4
Not yet recruiting NCT06212206 - PillBotâ„¢ - Remotely Controlled Capsule Endoscopy N/A
Not yet recruiting NCT03092414 - Linked Color Imaging Based CMV Diagnosis for Gastric Mucosal Lesions N/A
Not yet recruiting NCT06273319 - The Effect of Oxygen Application With Double Nasal Cannula on Respiratory Complications N/A
Not yet recruiting NCT02994472 - Gastric Emptying: in Vivo Studies in Healthy Volunteers N/A
Recruiting NCT03267355 - Indications and Outcomes of Endoscopic Ultrasound in Tanta N/A
Completed NCT01322737 - Feasibility Trial to Evaluate the Ability of the SuMO Tissue Access and Resection System N/A
Completed NCT04111393 - Transoral Removal of Specimen During Laparoscopic Gastric Resection
Recruiting NCT05249933 - Pronase Granules in Gastric Cleaning Phase 2/Phase 3
Completed NCT04479423 - The Usage of Soda-Water in Gastric Preparation for Magnetically Controlled Capsule Endoscopy N/A
Completed NCT05392452 - Fully Closed-Loop Insulin Delivery in Abdominal Surgery (CLAB) N/A
Not yet recruiting NCT05801055 - A Study to Evaluate Endoscopic Visibility of Stomach After a Combination Drink of N-acetylcysteine and Simethicone Phase 3