Clinical Trials Logo

Clinical Trial Summary

This clinical study has been initiated to assess the effect of laser exposure on human skin and determine the threshold for tissue damage. The tissue specific effects will be evaluated through histological evaluation. Excess skin from corrective surgery (gastric bypass or similar) will be donated for this study. Skin samples will be subjected to titrating laser treatment with varying laser intensity and exposure time.


Clinical Trial Description

The dosimetry of laser induced hyperthermia and threshold for tissue damage will be evaluated. A dose escalation study will be performed by varying irradiance (mW) and time (minutes). Surface temperature will be monitored concurrently. Acute lesions occurring within 5 minutes of irradiation will be assessed and histological damage will be observed microscopically in slice sections of punch biopsies and qualitative assessed. Irradiation regimes above the anticipated threshold will be employed to properly titrate the irradiation necessary to elicit a thermal damage response. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT03402347
Study type Interventional
Source RSP Systems A/S
Contact
Status Completed
Phase N/A
Start date January 1, 2019
Completion date June 16, 2019

See also
  Status Clinical Trial Phase
Recruiting NCT02708589 - The Effects of Probiotic Supplementation on the Results of Gastric Bypass Surgery Phase 2/Phase 3
Recruiting NCT03046147 - The Effect of Roux-en-Y Gastric Bypass on Bone Turnover N/A
Completed NCT01938469 - Effect of Meal Number, Frequency, and Form on Satiety and Metabolism After Weight Loss Surgery N/A
Withdrawn NCT01930448 - Mechanisms of Diabetes Control After Weight Loss Surgery, Sub-study #1 N/A
Completed NCT00571220 - Mechanisms of Diabetes Control After Weight Loss Surgery N/A
Withdrawn NCT00863993 - Energy Expenditure and Gastric Bypass Surgery N/A
Terminated NCT03201952 - Examination of the Metabolic Effects of Direct Bile Salt Delivery to the Ileum in Humans Phase 1