Trastuzumab Based Therapy in HER2 Positive AGC

Status Completed

Clinical Trial Summary

Trastuzumab plus chemotherapy is an effective therapy in HER2 positive advanced gastric cancer (AGC). However, the efficacy of routine trastuzumab therapy and its association with clinicopathologic factors remain unclear. The object of the study is to determine whether the addition of trastuzumab to first-line chemotherapy improves efficacy compared with chemotherapy alone in HER2 positive AGC.

Clinical Trial Description

A total of 98 patients with HER2 positive AGC were enrolled in this prospective observational study. All patients were treated with trastuzumab plus chemotherapy as the first line therapy. Efficacy and safety of trastuzumab were analyzed, clinical and pathological data were collected to evaluate the potential prognostic factors on progressive free survival. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03024450
Study type	Observational [Patient Registry]
Source	Shanghai Zhongshan Hospital
Contact
Status	Completed
Phase	N/A
Start date	January 2012
Completion date	December 2016

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