Gastric Adenocarcinoma Clinical Trial
Official title:
Predictive Value of Serum and Peritoneal CEA and CA 19-9 for TNM Stage and Peritoneal Dissemination of Gastric Adenocarcinoma
For preoperative staging and prediction of peritoneal dissemination of gastric adenocarcinoma, usage of serum and peritoneal levels of carcinoembryonic antigen (CEA) and CA 19-9 may be helpful. Additionally, the prognosis of the patients with gastric adenocarcinoma treated with gastrectrectomy may be associated with serum and peritoneal levels of tumor markers.
Clinical usage of tumor markers on preoperative staging and prediction of peritoneal
dissemination of gastric adenocarcinoma is a controversial issue. It has been thought that
there is a positive correlation between serum and peritoneal levels of carcinoembryonic
antigen (CEA) and CA 19-9 and pathologic features of gastric tumors and peritoneal
dissemination.
In this study, it was aimed to evaluate the effect of serum and peritoneal CEA and CA 19-9
to predict TNM stages and peritoneal washing cytology in patients with gastric
adenocarcinoma after curative gastrectomy, and to determine predictive value of these
measurements to the development of recurrence and death.
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