Clinical Trials Logo
  1. Home
  2. Gambling
  3. NCT03223896
  4. Details
NCT03223896 Clinical Trial

Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray

Gambling Clinical Trial

— NALPILO  

Official title:
Pilot Study: Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03223896
Other study ID # 67016.02.01/2016
Secondary ID
Status Completed
Phase Phase 2
First received
Last updated
Start date February 14, 2017
Est. completion date June 30, 2017

Study information
Verified date September 2019
Source National Institute for Health and Welfare, Finland
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Non-controlled pilot study. Two groups: Group A: naloxone nasal spray max 8 mg/per day; Group B: naloxone max 16 mg/per day. Study duration 8 weeks. Brief intervention.

Description:

Non-controlled pilot study. Two groups: Group A: naloxone nasal spray max 8 mg/per day; Group B: naloxone max 16 mg/per day. Study duration 8 weeks. No supportive therapy, but brief self-help booklet. Primary outcomes: adverse events, adherence and drop out analysis. Secondary outcome: gambling expenditure.

Recruitment information / eligibility
Status Completed
Enrollment 20
Est. completion date June 30, 2017
Est. primary completion date June 30, 2017
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- age over 18 years old

- South Oaks Gambling Scale (SOGS) 5 or over points

- possibility to keep a record with phone and send text messages

- fluent in Finnish Language

Exclusion Criteria:

- active drug use (specially opioids) current use - drugs screen

- nasal abnormality or mucosal irritability

- hepatitis c virus, kidney insufficiency

- psychosis, unstable mental health, risk suicide (Beck Depression Inventory)

- pregnancy and/or breast feeding

- persons according to Finnish Medical Law 188/1999 ยง7-10

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Naloxone hydrochloride 20mg/ml
Nasal spray

Locations
Country Name City State
Finland National Institute for Heath and Welfare Helsinki

Sponsors (1)
Lead Sponsor Collaborator
National Institute for Health and Welfare, Finland

Country where clinical trial is conducted

Finland, 

Outcome
Type Measure Description Time frame Safety issue
Primary Adverse events Diary 8 weeks
Primary Adherence Case Report Form 8 weeks
Secondary Gambling expenditure Money 8 weeks
See also
  Status Clinical Trial Phase
Not yet recruiting NCT02862821 - Biomarkers of Online Gambling Addiction N/A
Completed NCT00967005 - N-Acetyl Cysteine Plus Behavioral Therapy for Nicotine Dependent Pathological Gamblers Phase 2
Withdrawn NCT00370188 - Topiramate on Gambling-Related Behaviours Phase 2
Completed NCT00069420 - Cognitive Motivational Behavior Therapy for Gamblers Phase 1
Recruiting NCT05241041 - Effects of Positive Psychological Group Psychotherapy and Auricular Acupressure on Withdrawal Symptoms N/A
Completed NCT02841566 - Comparative Study of the Link Between the Practice of Gambling and Money and Materialism Among Problem Gamblers and Non-problem Gamblers N/A
Not yet recruiting NCT05630157 - Evaluation of Effectiveness of the Unplugged Program on Gambling Among Adolescents (GAPUnplugged) N/A
Completed NCT00118391 - Cognitive-Behavioral Treatment of Gambling Phase 1
Completed NCT03323606 - Online Interventions for Gamblers With and Without Co-occurring Problem Drinking N/A
Completed NCT01219426 - A Transversal Study for the French Validation of Two Assessment Tools of Gambling Related Cognitions. N/A
Completed NCT00158314 - Cognitive Behavioral Therapy for Treatment of Pathological Gambling Phase 1
Completed NCT02250586 - Internet Based Cognitive Behavior Therapy for Concerned Significant Others of Problem Gamblers N/A
Completed NCT02800096 - Online Interventions for Gamblers With and Without Co-occurring Mental Health Concerns N/A
Completed NCT00685048 - Brief Therapies for Problem Gambling Substance Abusers N/A
Completed NCT00078273 - Indicated Prevention With At-Risk Gamblers Phase 2
Recruiting NCT05933356 - Effectiveness of Exergames on Cognitive, Social Functionamong Chronic Schizophrenia N/A
Not yet recruiting NCT03493399 - Testing Interference-based Methods to Mitigate Gambling Craving - A Multiple Single Case Design N/A
Not yet recruiting NCT06171516 - Internet-based Cognitive Behavioral Therapy for Individuals With Gambling Disorder in Indonesia N/A
Recruiting NCT06195995 - Brain Mechanism and Intervention of Executive-control Dysfunction Among Gambling Disorder N/A
Recruiting NCT06341504 - Prevention Messages for EGMs: Effects on Behaviours and Cognitions N/A

External Links