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Gambling clinical trials

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NCT ID: NCT06467422 Not yet recruiting - Gambling Disorder Clinical Trials

Effects of Transcranial Temporal Interference Stimulation on Risky Decision-making and Impulse Control in Gambling Disorder

Start date: June 20, 2024
Phase: N/A
Study type: Interventional

The purpose of this research is to investigate the effect of transcranial temporal interference stimulation (tTIS) targeting the dorsal anterior cingulate cortex in patients with gambling disorder.

NCT ID: NCT06341504 Recruiting - Gambling Clinical Trials

Prevention Messages for EGMs: Effects on Behaviours and Cognitions

Start date: February 27, 2024
Phase: N/A
Study type: Interventional

The goals of this randomized controlled trial are to test the manifold effects of prevention pop-up messages on participants' behaviours, cognitions and affects. This study is conducted among regular EGMs' players (defined as having played EGMs at least once every two weeks for the past 12 months) who are not classified as probable pathological gamblers by the PGSI. After answering a series of short questionnaires by phone, participants are asked to schedule a gambling session which is done in a laboratory on the university's campus. This laboratory replicates a typical bar, and is equipped with real EGMs. Participants are recruited under the false pretense of giving their opinion on the realism of the bar replica, and on the overall feeling of the gambling session in it. They are told that: (a) they are free to gamble as much and for as long as they like; (b) they are allowed to take breaks; (c) gambling is to be done with their own money; (d) the only compensation for participation are the potential winnings made while gambling; (e) net winnings across their whole session are paid, but losses are real. There is only one participant at a time in the laboratory for the gambling session. After having stopped by their own volition (some exceptions apply, see "Detailed Description" for further details), participants are debriefed on the real goals of this study and reimbursed any incurred losses while gambling. They are then be asked to answer another series of questionnaires.

NCT ID: NCT06235333 Not yet recruiting - Gambling Problem Clinical Trials

Exploring a Lottery-promoted Gambling Disorder Screening Day Intervention

Start date: March 12, 2024
Phase: N/A
Study type: Interventional

The study is a randomized trial of gambling screening plus feedback (intervention) or gambling information (control) conditions, with data collection at baseline (T1) and a 3-month follow-up (T2). Two participant recruitment strategies (i.e., Hoosier Lottery cohort and MTurk Workers cohort) will allow the investigators to compare how recruitment source relates to post-intervention gambling behavior change intentions and assorted gambling-related behavior changes. The investigators also seek to understand how experiences with screening vary for minoritized and non-minoritized people who gamble.

NCT ID: NCT06230809 Not yet recruiting - Problem Gambling Clinical Trials

Internet Based Self-help for Problem Gambling Concerned Significant Others

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

The project aims to evaluate a brief online self-help intervention for Concerned Significant Others of individuals with Problem Gambling. The intervention consists of five modules with texts, films and exercises and is compared to a waiting list.

NCT ID: NCT06195995 Recruiting - Gambling Clinical Trials

Brain Mechanism and Intervention of Executive-control Dysfunction Among Gambling Disorder

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

The investigators assume that transcranial Alternating Current Stimulation (tACS) could improve gambling disorder patients' executive-control function by adjusting the synchronization patterns and enhancing the functional connectivity of the prefrontal-ventral striatum pathway. This study intends to test the effect of tACS treatment. Three-month follow-up assessment will be conducted to test the changing of the executive-control function and its mechanism.

NCT ID: NCT06182137 Not yet recruiting - Gambling Disorder Clinical Trials

Repetitive Transcranial Magnetic Stimulation (rTMS) in The Treatment of Gambling Disorder in Indonesia

Start date: January 2024
Phase: N/A
Study type: Interventional

Research has shown that cognitive-behavioral therapy (CBT) is an effective treatment for gambling disorder. Several studies had also been done to evaluate the effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) in addiction management, particularly in alleviating craving. A randomised controlled trial (RCT) of 60 subjects would be conducted to evaluate the effectiveness of transmodalistic therapy with a combination of rTMS and CBT for online gambling disorder.

NCT ID: NCT06171516 Not yet recruiting - Gambling Clinical Trials

Internet-based Cognitive Behavioral Therapy for Individuals With Gambling Disorder in Indonesia

ICBT
Start date: January 2024
Phase: N/A
Study type: Interventional

Gambling disorder (GD) has become a wide concern in Indonesia, as many negative consequences aroused from this psychiatric condition. Prompt treatment with appropriate method of delivery is required to achieve optimal outcome in GD patients. This study aims to determine the effectiveness and feasibility of internet-based cognitive behavioral therapy (iCBT) in treating GD. This non-randomised pilot and feasibility study will recruit 20 people with GD. All participants will receive the iCBT intervention through self-learning videos and guided weekly group sessions. The effectiveness of the intervention will be assessed at baseline (week 0), post-treatment completion (week 10), and 6 weeks post-treatment (week 16). Expanded access of the iCBT module will not be available until after the study completion.

NCT ID: NCT06122298 Not yet recruiting - Gambling Addiction Clinical Trials

Testing the Interplay of Gambling, Emotion and Reward

TIGER
Start date: April 30, 2024
Phase:
Study type: Observational

Background The nature and direction of dysfunctional reward processing in gambling disorder remains unclear. We aim to test a novel neurobiological model of gambling addiction, that takes into account inter-individual differences, as well as the multifactorial nature of gaming addiction. Objectives Primary objective: This project will test the hypothesis that there are two opposite brain phenotypes that characterize two distinct subpopulations of gamblers, so-called impulsive vs. emotional, respectively. Secondary objective: This project will also seek to determine whether the brain phenotypes proposed above are capable of predicting gambling behavior outside the laboratory. Study design The primary objective will be tested using a reward task and a facial emotion recognition task performed by participants in an fMRI scanner. The secondary objective will be tested by combining fMRI measures with behavioral measures from everyday life collected via Ecological Momentary Assessment (EMA). Study population This study will focus on individuals with gambling problems, as well healthy subjects with no gambling problems and no psychiatric comorbidities. Outcomes/Endpoints Primary endpoint: We will compare striatum and amygdala reactivity between the three groups of impulsive gamblers, emotional gamblers and healthy subjects. Secondary endpoint: We will assess the correlation between emotional states and gambling behavior in everyday life, based on striatum and amygdala reactivity, using multiple linear regression models.

NCT ID: NCT06107621 Recruiting - Clinical trials for Comorbidities and Coexisting Conditions

iCBT for GD and Comorbidities - a Pilot

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

The study is a pilot study (Total N=30), with at pre, weekly during treatment, post and at three-month follow-up.

NCT ID: NCT06099522 Recruiting - Gambling Disorder Clinical Trials

Internet-CBT for Gambling Disorder - a Randomized Controlled Trial

Start date: January 15, 2024
Phase: N/A
Study type: Interventional

The study is a randomized controlled trial (Total N=150; each condition n=75) of internet-based cognitive behavioral therapy (iCBT), with measures at pre, weekly during treatment, post, three and at six month follow-up. Participants will be assigned to either standard iCBT and "Spelpaus" (treatment condition), or "Spelpaus" only (control condition).