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Gallstones clinical trials

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NCT ID: NCT01009450 Completed - Clinical trials for Gall Bladder Stone in Cirrhotics

Clipless Laparoscopic Cholecystectomy Using Harmonic Scalpel in Cirrhotic Patients a Prospective Randomized Study

CLC
Start date: August 2008
Phase: N/A
Study type: Interventional

This study included group (A) (60 patients with liver cirrhosis and complaining of gall stone) in whom LC was done using traditional method (TM) by clipping both cystic duct and artery and dissection of gall bladder from liver bed by diathermy, and group (B) (60 patients with liver cirrhosis and complaining of gall stone) LC was done using harmonic scalpel (HS) closure and division of both cystic duct, artery and dissection of gall bladder from liver bed by harmonic scalpel. The Intraoperative and postoperative parameters were collected included duration of operation, postoperative pain, and complications.

NCT ID: NCT00986544 Completed - Cholelithiasis Clinical Trials

Drain After Elective Laparoscopic Cholecystectomy

Start date: December 2009
Phase: N/A
Study type: Interventional

The trial aims to assess the value of drains in elective laparoscopic cholecystectomy.

NCT ID: NCT00984100 Completed - Cholelithiasis Clinical Trials

Natural Orifice Translumenal Endoscopic Surgery (NOTES) Transvaginal Cholecystectomy

Start date: January 2009
Phase: N/A
Study type: Interventional

Natural Orifice Translumenal Endoscopic Surgery (NOTES) describes a new field of investigational surgery which uses the endoscope as the primary operative tool. The insertion sites for the endoscope include natural orifices such as the mouth, anus, vagina, or urethra. Multidisciplinary teams of surgeons and gastroenterologists collaborate to develop safe and effective surgical techniques via the natural orifice route in order to avoid surgical incisions. Early studies have focused on transvaginal surgery as the access route to the abdomen as it sidesteps troubling questions about infection and closure of the organ. This study is a pilot study to test the feasibility to NOTES transvaginal cholecystectomy using conventional surgical and endoscopic tools.

NCT ID: NCT00981604 Completed - Cholelithiasis Clinical Trials

Single Incision Laparoscopic Surgery (SILS) Versus Laparoscopic Cholecystectomy

SILS
Start date: August 2009
Phase: N/A
Study type: Interventional

Prospective randomized trial of single incision versus standard 4 port laparoscopic cholecystectomy. Hypothesis is that the operative time will be longer with single incision.

NCT ID: NCT00974194 Completed - Cholecystolithiasis Clinical Trials

Safety and Cost-effectiveness Study of Single Port Laparoscopic Cholecystectomies

SPoCOT
Start date: September 2009
Phase: N/A
Study type: Interventional

Many feasibility studies have been published on Single Port surgery, but no comparative studies have shown any advantages compared to standard laparoscopy. The purpose of this study is to compare the clinical outcomes and economical issues of laparoscopic cholecystectomies using single port transumbilical approach and three trocars.

NCT ID: NCT00971750 Completed - Ultrasonography Clinical Trials

Laparoscopic Versus Transabdominal Ultrasound in Morbidly Obese Patients

Start date: October 2003
Phase: N/A
Study type: Observational

The objective of this study is to prospectively compare laparoscopic ultrasound to transabdominal ultrasound for the detection of gallbladder pathology in obese patients presenting for laparoscopic gastric bypass. We hypothesize that laparoscopic ultrasound will be more sensitive and specific for cholelithiasis than transabdominal ultrasound in morbidly obese patients.

NCT ID: NCT00940264 Completed - Cholecystitis Clinical Trials

Laparoscopic Transvaginal Hybrid Cholecystectomy: a Prospective Data Collection.

Start date: September 2008
Phase: N/A
Study type: Observational

Transvaginal hybrid procedures especially the transvaginal hybrid cholecystectomy are of interest as an available NOTES-Procedure for the clinical routine. Few authors have demonstrated the feasibility and safety in a selected patient collective. The aim of this prospective data collection is to evaluate the feasibility in the clinical routine in a non select patient collective. Therefore all patients giving the informed consent to the transvaginal hybrid cholecystectomy will be included and assessed concerning feasibility to perform the transvaginal approach and complete the operation transvaginally.

NCT ID: NCT00910325 Terminated - Cholelithiasis Clinical Trials

Natural Orifice Translumenal Endoscopic Surgery: Laparoscopic-Assisted Transvaginal Cholecystectomy

Start date: November 2008
Phase: Phase 1/Phase 2
Study type: Interventional

To determine the feasibility, safety, and efficacy of a novel minimally invasive approach to cholecystectomy and to establish a description of this novel translumenal technique in humans at this institution.

NCT ID: NCT00904865 Recruiting - Cholecystitis Clinical Trials

Single Port Access (SPA) Cholecystectomy Versus Standard Laparoscopic Cholecystectomy

Start date: February 2009
Phase: Phase 2/Phase 3
Study type: Interventional

Background: Single port access surgery is a rapidly progressing surgical approach which allows performance of standard laparoscopic surgery through a single transparietal port instead of multiple port accesses. Objective: Demonstrate the validity of Single port access (SPA) cholecystectomy compared to multiple ports laparoscopic cholecystectomy. Hypothesis: SPA cholecystectomy is associated with decreased parietal and body image trauma compare to multiple ports laparoscopic cholecystectomy. SPA cholecystectomy should be associated with better cosmetic results, may improve postoperative recovery due to lower parietal pain. SPA cholecystectomy may also be associated with decreased rate of parietal complications as lower numbers of transparietal port are placed. Methods: All patients offered cholecystectomy, either SPA or multiport cholecystectomy, included in the study will have recognized biliary pathology for which formal indication cholecystectomy are recognized internationally. Surgical technique, either for SPA cholecystectomy or for multiple ports cholecystectomy, will be the same except, that one surgical technique is achieved through a single transparietal port and the other through multiple ports. Randomization will be performed before surgeries after patients have given their informed consent to the study. No specific test or cost will be necessitated by the study. Patients will be informed orally and will receive a short study summary, allowing them to give an informed consent. Endpoints: - Morbidity - Body image and Cosmetic results - Post-operative pain (opioid sparing effect) - Operative time - Hospital stay

NCT ID: NCT00890201 Completed - Clinical trials for Pancreaticobiliary Reflux

Pancreaticobiliary Reflux in Patients Without Cholelithiasis

Start date: January 2009
Phase: N/A
Study type: Observational

Pancreaticobiliary reflux has been found in patients with cholelithiasis and gallbladder cancer associated with normal pancreaticobiliary union. However, the presence of pancreaticobiliary reflux has not been studied in patients without gallstones (healthy gallbladders). The authors believe that pancreaticobiliary reflux might be a normal phenomenon in patients with and without gallstones, although in patients with cholelithiasis it might constitute a pathological condition associated with dismotility of the biliary tree and the sphincter of Oddi.