Clinical Trials Logo
  1. Home
  2. Gallstone
  3. NCT01998451
  4. Details
NCT01998451 Clinical Trial

The Discovery of the Double Sphincter in Gallbladder

Gallstone Clinical Trial

Official title:
The Discovery of the Double Sphincter in Gallbladder

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01998451
Other study ID # GYGDWK-03
Secondary ID
Status Recruiting
Phase Phase 4
First received November 13, 2013
Last updated March 6, 2016
Start date December 2012
Est. completion date December 2018

Study information
Verified date March 2016
Source The First Affiliated Hospital of Guangzhou Medical University
Contact Chengyi Sun, M.D.
Phone +86 851-6771326
Email 139724558@qq.com
Is FDA regulated No
Health authority United States: Food and Drug Administration
Study type Interventional

Clinical Trial Summary

We found a new Double sphincter which located in the neck of gallbladder，we supposed it may be related to control pressure of bile duct.Its formation is related to genetic factors.

Description:

To contrast the recurrence rate of gallstones between patients with gallbladder double sphincter and patients with general gallbladder sphincter who underwent the treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation. Method:Patients with gallbladder double sphincter and patients with general gallbladder sphincter who underwent the treatment of cholecystolithiasis by minimally invasive cholecystolithotomy with gallbladder reservation in The Affiliated Hospital of Guiyang Medical College from May 2012 to December 2015. We collect these patients' bile during surgery.Patients with gallbladder double sphincter as trial group, patients with general gallbladder sphincter as control group.the overall follow-up period is 3 years. Then the investigators statistically analyze improvement of cholecystolithiasis symptoms, thickness of gall bladder wall, the gallbladder function and the rate of the recurrence of cholesterol gallstone in 2 groups.we also analysis of the genetic differences from bile between two groups.

Recruitment information / eligibility
Status Recruiting
Enrollment 150
Est. completion date December 2018
Est. primary completion date December 2018
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 15 Years to 70 Years
Eligibility Inclusion Criteria:

- people with gallbladder double sphincter

Exclusion Criteria:

- people without gallbladder double sphincter

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Single Blind (Subject), Primary Purpose: Prevention

Related Conditions & MeSH terms

Intervention

Drug:
• Tauroursodeoxycholic acid
patients from double sphincter group and general gallbladder sphincter group all received Tauroursodeoxycholic acid after surgery for 6 months.

Locations
Country Name City State
China The Discovery of the Double Sphincter in Gallbladder Guiyang Guizhou

Sponsors (1)
Lead Sponsor Collaborator
The First Affiliated Hospital of Guangzhou Medical University

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary The Discovery of The Double Sphincter in Gallbladder The gallbladder of some gallstone patients contain a new Anatomical structure named Double sphincter which located in the middle of gallbladder,we supposed it may be related to the formation of gallstone and pressure of bile duct.Its formation is related to genetic factors. All the patients will be follow-up for an expected average of 3 years. Yes
See also
  Status Clinical Trial Phase
Completed NCT02738710 - Comparison of Post-operative Pain at Umbilical Wound After Laparoscopic Cholecystectomy With Transumbilical Versus Infraumbilical Incision N/A
Completed NCT04390828 - Effectiveness of Guided Imagery Meditation in Patients With Laparoscopic Gallstone Surgery N/A
Recruiting NCT01383031 - Safety and Efficacy Study of Transumbilical Laparoendoscopic Single Site Cholecystectomy Phase 2/Phase 3
Completed NCT04122261 - A Clinical Study of Chinese Domestic Surgical Robot N/A
Completed NCT04879459 - Impact on Diagnostic Accuracy of a Specific Clinical Ultrasound Practical Teaching
Completed NCT04145843 - Treatment Outcomes in Bile Duct Stones
Recruiting NCT04350346 - The Comparative Analysis Between Motilitone and Gasmotin for the Symptom Relief in Gallstone Patients With Functional Dyspepsia N/A
Recruiting NCT03326154 - Post-Cholecystectomy Quality of Life
Completed NCT03470584 - Vegetarian Diet and Chronic Degenerative Diseases
Recruiting NCT04970030 - Comparison Between Mechanical Intracanal (ML) Lithotripsy and Electrohydraulic Intracolangioscopic (EHL) Lithotripsy in the Treatment of Difficult Main Biliary Tract Lithiasis N/A
Active, not recruiting NCT06223061 - Global Evaluation of Cholecystectomy Knowledge and Outcomes
Recruiting NCT05965466 - The Incidence of Gallstones After Gastrectomy N/A
Completed NCT04980417 - Concomitant Versus Delayed Cholecystectomy for Management of Obesity With Gallstone N/A
Recruiting NCT04915651 - Gallbladder Cryoablation in High-Risk Patients N/A
Completed NCT02808546 - The Risk Factors of Symptomatic Gallbladder Stone: Age-Sex Matched Case-control Study Performed in Single Institute N/A
Not yet recruiting NCT00792389 - Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies Phase 4
Recruiting NCT06287931 - Probiotics for Gallstones in Post-bariatric Surgery Patients N/A
Terminated NCT03852836 - Evaluation of MRI Sequences for Ultra-rapid Acquisition of Bile Ducts Images N/A
Not yet recruiting NCT05704907 - Diagnostic Performance of Dual Energy CT for the Detection of Gallbladder Gallstones N/A
Completed NCT03804775 - Comparative Analysis of Serum Lipid Profiles in Patients With and Without Gallstones