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Gallbladder clinical trials

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NCT ID: NCT03510923 Completed - Cholecystectomy Clinical Trials

Selective Rather Than Routine Histopathological Examination Following Appendectomy and Cholecystectomy

FANCY
Start date: May 1, 2018
Phase:
Study type: Observational

The FANCY study will investigate whether a selective policy of histopathological examination of appendices and gallbladders based on the intraoperative findings of the surgeon is safe and cost-effective.

NCT ID: NCT01981343 Completed - Gallbladder Clinical Trials

A Parallel Study Evaluating the Effect of A-F Betafood® on Gallbladder and Liver Function.

Start date: November 11, 2013
Phase: Phase 2
Study type: Interventional

Gallstone formation is multifactorial: immutable risk factors include genetics and ethnicity, age and being female, and mutable risk factors include obesity, and metabolic syndrome, diet, rapid weight loss, and other conditions such as cirrhosis, Crohn's disease, irritable bowel syndrome, gallbladder stasis, and the use of certain drugs like Ceftriazone. Previous studies have linked serum cholesterol, and low-density lipoprotein cholesterol levels and fatty liver disease to gallbladder disease. Given betaine's reported beneficial effects on fatty liver and lipid profile, A-F Betafood® may have a beneficial effect on gallbladder function. The objective of the study is to assess the effect of A-F Betafood® on gallbladder and liver function as measured by gallbladder ultrasounds and liver function tests. The hypothesis is that A-F Betafood® will improve gallbladder and liver function after the 12 week treatment period. This is a single-center, randomized, double-blind, placebo-controlled, parallel group study with two arms. This study will consist of a single 12 week treatment period. The planned sample size for this study is 50 overweight female subjects, with 25 subjects randomized equally to each of the two study arms in double-blind manner at a ratio of 1:1