Clinical Trials Logo
  1. Home
  2. Gallbladder Diseases
  3. NCT04563260

Effect of Palonosetron on Remifentanil for Preventing Emergence Cough in Female

Gallbladder Diseases Clinical Trial

Official title:
Effect of Palonosetron on Effect-site Concentration of Remifentanil for Preventing Emergence Cough During General Anesthesia in Female Patients Undergoing Laparoscopic Cholecystectomy

Clinical Trial Summary

The primary purpose of this study is to investigate the optimal Ce of remifentanil for preventing emergence cough following extubation during general anesthesia in female patients who receive the palonosetron or not.

Clinical Trial Description

Remifentanil is a potent ultrashort-acting opioid, with rapid onset and offset of drug effect. It allows rapid anesthetic emergence even after a prolonged infusion, and decreases the at-risk time during extubation. In addition, cough suppression of remifentanil enables smooth extubation with reduced complications. However, the infusion of remifentanil suppresses the emergence cough effectively in clinical practice, whereas it still delays the awakening from anesthesia, resulting in prolonged emergence time. Reduced Ce of remifentanil during emergence would decrease the adverse events that are associated with remifentanil infusion. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04563260
Study type Interventional
Source Ajou University School of Medicine
Contact
Status Completed
Phase N/A
Start date October 7, 2020
Completion date March 19, 2021
View Details
See also
  Status Clinical Trial Phase
Completed NCT00370344 - Small-incision Open Cholecystectomy or Laparoscopic Cholecystectomy for Gallbladder Disease Phase 2/Phase 3
Recruiting NCT05900037 - GATT-Patch Versus SURGICEL® Original in Minimally Invasive Liver and Gallbladder Surgery N/A
Withdrawn NCT02827097 - The Effect of Rectus Sheath Block on the Postoperative Analgesia in the Patients Undergoing Robotic Single Port Cholecystectomy N/A
Completed NCT03327688 - Point-of-care Ultrasound in Finland N/A
Completed NCT00388830 - Emergency Ultrasound of the Gallbladder N/A
Completed NCT03583021 - Sugammadex on Remifentanil Ce for Preventing Emergence Cough in Male N/A
Completed NCT02956252 - Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy N/A
Completed NCT00552162 - NOTES Transvaginal Cholecystectomy and Appendectomy N/A
Completed NCT04409652 - Head Position on Preventing Emergence Cough N/A
Recruiting NCT04324515 - Randomized Trial Comparing Gastric Bypass With and Without Cholecystectomy N/A
Recruiting NCT04915651 - Gallbladder Cryoablation in High-Risk Patients N/A
Completed NCT01413633 - A Novel Technique For Gall Bladder Fundus Retraction In Single Incision Laparoscopic Cholecystectomy N/A
Terminated NCT00040131 - Safety and Efficacy Study of IL-10 (Tenovil TM) in the Prevention of Post-ERCP Acute Pancreatitis (Study P02580)(TERMINATED) Phase 2
Completed NCT02827136 - Effect of Lidocaine Patch for Shoulder Pain in Laparoscopic Cholecystectomy N/A
Completed NCT06244589 - Evaluation of Risk Factors Leading to Conversion From Laparoscopic Cholecystectomy to Open Surgery N/A
Completed NCT03888976 - Cholecystoduodenal Fistula With and Without Gallstone Ileus
Withdrawn NCT03160157 - Comparing the Outcomes of Laparoscopic Cholecystectomy vs. Robotic Cholecystectomy
Completed NCT04407078 - Sugammadex on Remifentanil Ce for Preventing Emergence Cough in Female N/A
Not yet recruiting NCT04922528 - Visualization of the Extrahepatic biliaRy Tree Trial N/A
Not yet recruiting NCT06315179 - Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation (STRIDE)