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Gallbladder Diseases clinical trials

View clinical trials related to Gallbladder Diseases.

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NCT ID: NCT04025645 Completed - Biliary Disease Clinical Trials

Common Bile Duct Pressures in Patients With and Without Cholelithiasis

Start date: January 1, 2015
Phase:
Study type: Observational

Objective. To measure the pressures of the common bile duct in patients with and without cholelithiasis and relating them to the presence of pancreatobiliary reflux. Summary Background Data. The reflux of pancreatic enzymes into the epithelium of the bile duct and mainly of the gallbladder is an abnormal phenomenon that plays a role in the lithogenesis and carcinogenesis of this epithelium. It has been suggested that the cause of this reflux is the dysfunction of the sphincter of Oddi. Because the pressure of the common bile duct depends on the pressures of the sphincter of Oddi, this dysfunction would be reflected in an increase in the pressure of the common bile duct in patients with cholelithiasis. Methods. A prospective case-control study was designed. The universe was constituted by a convenience sample in which all patients undergoing gastrectomy for gastric cancer during 30 months in our institution were included. The primary outcome measure was to establish differences between common bile duct pressures in patients with and without cholelithiasis. Results. Common bile duct pressures in patients with gallstones showed a significant elevation (Mean 16.9 mmHg) compared to those of patients without gallstones (Mean 3.3 mm Hg) (p<0.0001). These pressures correlated with the values of amylase and lipase in gallbladder bile; higher levels of these enzymes were found in patients with gallstones compared to patients without gallstones (p<0.0001). Conclusions. Common bile duct pressures in patients with cholelithiasis were significantly elevated above the parameters previously considered normal.

NCT ID: NCT03888976 Completed - Clinical trials for Gallbladder Diseases

Cholecystoduodenal Fistula With and Without Gallstone Ileus

Start date: February 1, 2019
Phase:
Study type: Observational

Observative and descriptive study of 10 patients, which were diagnosed with a Cholecystoduodenal fistula, All electronic medical records were retrospectively reviewed.

NCT ID: NCT03698266 Completed - ERCP Clinical Trials

Is Needle Knife Fistulotomy An Effective First Step Strategy For All ERCPs?

Start date: November 23, 2018
Phase: N/A
Study type: Interventional

Participants in this study will be undergoing a procedure called an endoscopic retrograde cholangiopancreatography (ERCP). This procedure is most commonly performed to help treat conditions affecting specific areas of the digestive system called the pancreas and bile ducts. Patients will consent to allow the study physician to access these areas of the digestive system by making a cut using a technique called a needle-knife fistulotomy. If the physician is unable to gain access through this method, they will make the cut using a technique called a sphincterotomy.

NCT ID: NCT03583021 Completed - Clinical trials for Gallbladder Diseases

Sugammadex on Remifentanil Ce for Preventing Emergence Cough in Male

Start date: June 25, 2018
Phase: N/A
Study type: Interventional

The primary purpose of this study is to investigate the optimal Ce of remifentanil for preventing emergence cough following extubation during general anesthesia in male patients who are reversed with sugammadex or neostigmine.

NCT ID: NCT03327688 Completed - Clinical trials for Deep Vein Thrombosis

Point-of-care Ultrasound in Finland

Start date: October 20, 2017
Phase: N/A
Study type: Interventional

This study has two aims. 1. Deep venous thrombosis (DVT) is a common suspected medical condition. If it cannot be excluded clinically and using D-dimer, ultrasound examination is required. An option for traditional radiologist-performed ultrasound is a 2-point compression ultrasound (2-CUS). The safety of this technique is proven. However there does not exist any data on costs comparing traditional and 2-CUS pathways in primary health care. This study will evaluate the total cost of both pathways by conducting a cost-minimization analysis. It will also study the effect of a simple ultrasound education on the referrals to hospital due to suspected DVT. Hypothesis 1: Short education in ultrasound will reduce significantly referrals to hospital and save resources. 2. Length of stay (LOS) in emergency department (ED) is related to increased mortality, morbidity, prolonged hospital stay and probably patient satisfaction. LOS of patients with a point-of-care ultrasound (POCUS) performed by an emergency physician (EP) will be compared to those that have a radiology performed ultrasound examination. Further examination and accuracy of POCUS will be noted. Hypothesis 2: POCUS can shorten LOS significantly in selected clinical conditions

NCT ID: NCT02956252 Completed - Cholecystitis Clinical Trials

Spinal Versus General Anesthesia for Laparoscopic Cholecystectomy

Start date: June 2008
Phase: N/A
Study type: Observational

The aim of this study is to compare early postoperative outcomes of unselected consecutive patients underwent laparoscopic cholecystectomy (LC) under spinal versus general anesthesia.

NCT ID: NCT02827136 Completed - Clinical trials for Gallbladder Diseases

Effect of Lidocaine Patch for Shoulder Pain in Laparoscopic Cholecystectomy

Start date: February 8, 2017
Phase: N/A
Study type: Interventional

The primary purpose of this study is to investigate the effect of lidocaine patch on the shoulder pain score after end of surgery. The secondary purpose of this study is to investigate the effect of lidocaine patch on the total number of analgesic request on ward.

NCT ID: NCT02682368 Completed - Biliary Disease Clinical Trials

Multicentric Point of Care UltraSound by Surgeons Trial

POCUSS
Start date: October 1, 2015
Phase:
Study type: Observational

Acute gallbladder pathology and acute diverticulitis are common conditions met in emergency departments and comprise the bulk of admissions throughout general surgical calls. Both entities need imagistic description to tailor further management, which may be not readily available at the moment of patient's presentation. These delays may lose the window of opportunity for timed, quality decision making and may induce increased length of stay and subsequent increased costs. Ultrasound scanning has become very popular over the last half century and the equipment has become more compact, of a higher quality and less expensive, which has facilitated the growth of point-of-care ultrasonography - POCUS - that is, ultrasound performed and interpreted by the clinician at the bedside. The concept of an 'ultrasound stethoscope' is rapidly moving from theory to reality. There are a number of studies and case reports that are highlighting the advantages of POCUS, but still common grounds need to be sought after. Some countries, like USA and Germany, incorporate basic ultrasound in their resident's curriculum among different specialties. In the author's knowledge and based on the literature, there are a few-second-to-none studies regarding POCUS involving strictly the surgeons. The hypothesis of this study is that, surgeon performed ultrasound can be as accurate as the radiologists' findings for basic diagnostics in the aforementioned pathology, leading to real time decision making in the benefit of the patient. The closing remark is that by learning and doing these procedures the surgeon performing POCUS doesn't undermine his/her radiologist colleague's authority and skill. The big picture is that some basic tasks are transferrable and if used in an appropriate and methodical manner the final common goal - the benefit of the patient - is readily achieved.

NCT ID: NCT02049983 Completed - Clinical trials for Benign Gallbladder Disease

Levita Magnetic Grasper Device Safety and Performance Study

Start date: January 2014
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the Levita Magnetic Grasper Device Safety and Performance in Laparoscopy.

NCT ID: NCT01938040 Completed - Gallbladder Disease Clinical Trials

Effect IV Ibuprofen and Inflammatory Responses

Start date: May 2013
Phase: Phase 4
Study type: Interventional

This study is being done because the investigators wish to study ways to improve recovery after surgery. Injury, including surgical injury, causes inflammation. Inflammation is the body's attempt to protect itself and to start the healing process. Some surgical complications are related to the body's natural inflammatory response. Although mainly a healing response, inflammation can also have side effects which delay recovery. The investigators wish to determine the effect of a medication known as ibuprofen on recovery. You may know ibuprofen by the name Advil or Motrin. The medication will be given through the vein prior to the start of the surgery. Three blood samples will be taken, two while the patient is under anesthesia. The subject will be asked to complete several questionnaires.