Gallbladder Cancer Clinical Trial
Official title:
A Phase II Study of Gemcitabine and Cisplatin Plus Sorafenib in Patients With Advanced Biliary Tract Carcinomas Naïve to Systemic Therapy
The purpose of this study is to test an investigational combination of drugs for bile duct
or gallbladder cancers.
Gemcitabine and cisplatin are two forms of chemotherapy commonly used in combination to
treat bile duct and gallbladder cancers. We are looking to improve treatment results. We
will attempt to do so by adding sorafenib (a type of monoclonal antibody) to your treatment
plan. Sorafenib acts by attaching to blocking specific targets on cells. These targets may
help the cancer cells grow and divide. This study will help answer the question of whether
sorafenib is a helpful drug in patients with bile duct or gallbladder cancers when given
with gemcitabine and cisplatin.
This study is a phase 2 study. The purpose of a phase 2 study is to find out what effects,
good and/or bad, sorafenib in combination with gemcitabine and cisplatin has on advanced
bile duct and gallbladder cancers.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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