Gait Disorders, Neurologic Clinical Trial
Official title:
Correlation Between Gait Disorders and Neuropsychological Profile in Patients With Alzheimer's Disease and Lewy Body Disease
The prevalence of neurodegenerative diseases will increase over the next decades driven by
ageing population. It seems important to develop reliable, replicable and accessible
diagnostic tools.
This is a prospective study whose objective is to study the spatio-temporal parameters of
gait in patients with Alzheimer's and Lewy body diseases. 64 patients were included in this
study. A comparison of the two pathologies was conducted, followed by an analysis based on
four groups (mild, severe Alzheimer's disease, mild, severe Lewy body disease) and a study of
the severity of the diseases. To study these parameters, we used the Gaitrite treadmill.
The analysis of spatio-temporal parameters of walking in Alzheimer's disease and Lewy body
disease enables to identify discriminating variables between the two pathologies. The
probability of suffering from an Alzheimer's disease decreases with the pace increase but
increases with variations in length of the step, and with the rotation of the foot. While the
probability of suffering from Lewy body disease increases with the pace, variations in the
step duration, and the duration of double support.
These results are interesting but do not allow to establish a diagnostic score for these two
diseases. The monitoring of the variations of these parameters at individual level would
probably be more relevant and would enable to detect dual pathologies.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03593512 -
Deep Brain Stimulation for Autonomic and Gait Symptoms in Multiple System Atrophy
|
N/A | |
| Completed |
NCT04117737 -
A Pilot Study of Virtual Reality and Antigravity Treadmill for Gait Improvement in Parkinson
|
N/A | |
| Recruiting |
NCT04265482 -
Community-based Cohort of Functional Decline in Subjective Cognitive Complaint Elderly
|
||
| Completed |
NCT03192046 -
Bracing for Walking in Parkinson's Disease
|
N/A | |
| Terminated |
NCT01678547 -
Robot Walking Rehabilitation in Stroke Patients
|
N/A | |
| Recruiting |
NCT05510739 -
Support for Physical Activity in Everyday Life With Parkinson's Disease
|
N/A | |
| Recruiting |
NCT05417399 -
Influence of Hawthorne Effect and Dual-tasks on Gait in CP
|
||
| Completed |
NCT05683925 -
Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Gait Characteristics in Parkinson's Disease
|
N/A | |
| Recruiting |
NCT05110053 -
Spinal Cord sTimulation thEraPy for Parkinson's Disease Patients With Gait Problems
|
Phase 1 | |
| Recruiting |
NCT05801874 -
Gait and Posture Analysis in Hemiparetic Patients Through Optoelectronic Systems, "Smart" Tools and Clinical Evaluation
|
||
| Recruiting |
NCT04137146 -
SNS for Treatment of PD Gait Disorder
|
N/A | |
| Terminated |
NCT05622786 -
Effect of High-Intensity Gait Training Using a Treadmill on Locomotion Recovery in Traumatic Brain Injury Patients
|
N/A | |
| Recruiting |
NCT04855825 -
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
|
N/A | |
| Recruiting |
NCT05022147 -
Enhancing Gait Using Alternating-Frequency DBS in Parkinson Disease
|
Phase 1 | |
| Completed |
NCT04266743 -
FeetMe® Monitor: Alternative for the Evaluation of Gait Speed After Stroke
|
N/A | |
| Completed |
NCT04622657 -
Validity Reliability of The Dubousset Functional Test in Parkinson Disease
|
N/A | |
| Completed |
NCT02356536 -
The Effect of a Wearable Cueing Device on Freezing of Gait in Parkinson's Disease
|
Phase 1 | |
| Completed |
NCT01108029 -
Study of Memantine for Gait Disorders And Attention Deficit In Parkinson's Disease
|
Phase 4 | |
| Completed |
NCT00914095 -
Study of Methylphenidate to Treat Gait Disorders And Attention Deficit In Parkinson's Disease (PARKGAIT-II)
|
Phase 4 | |
| Completed |
NCT03314610 -
Effect of Need to Void on Parkinsonian Gait
|