G6PD Deficiency Clinical Trial
Official title:
Effects of Alpha Lipoic Acid Supplementation in G6PD Deficient Individuals After Acute Exercise
Verified date | November 2017 |
Source | University of Thessaly |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to investigate the effects of alpha-lipoic acid supplementation on redox status, physiological and biochemical parameters in G6PD deficient individuals after acute exercise.
Status | Completed |
Enrollment | 10 |
Est. completion date | July 2017 |
Est. primary completion date | July 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 65 Years |
Eligibility |
Inclusion Criteria: - G6PD deficiency Exclusion Criteria: - Any uncontrolled health condition for which exercise is contraindicated - Current use of dietary supplements or drugs - Pregnant, pregnancy intention or breast feeding |
Country | Name | City | State |
---|---|---|---|
Greece | Department of Physical Education & Sport Science of the University of Thessaly | Trikala | Karyes |
Lead Sponsor | Collaborator |
---|---|
University of Thessaly |
Greece,
Georgakouli K, Deli CK, Zalavras A, Fatouros IG, Kouretas D, Koutedakis Y, Jamurtas AZ. ?-lipoic acid supplementation up-regulates antioxidant capacity in adults with G6PD deficiency. Food Chem Toxicol. 2013 Nov;61:69-73. doi: 10.1016/j.fct.2013.01.055. Epub 2013 Feb 14. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in redox status after exercise | Indices of blood redox status | Before, immediately after and 1 hour after each trial of exercise | |
Secondary | Body composition | Body fat percentage | Before and after 4 weeks of alpha-lipoic acid supplementation, before and after 4 weeks of placebo | |
Secondary | Blood pressure | Blood pressure at rest | Before and after 4 weeks of alpha-lipoic acid supplementation, before and after 4 weeks of placebo |
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