Ileus Clinical Trial
Official title:
The Use of Oral Naloxone to Prevent Post Spinal Fusion Ileus
Postoperative ileus and opioid induced constipation are well-known post-operative complications. Previously, research has shown that using peripherally acting opioid antagonists can help alleviate the condition. There has not been a prospective study to investigate whether use of peripherally acting opioid antagonists are effective in preventing post-operative ileus in patients having spinal fusion surgeries.
Post operative ileus is a well-known complication following spinal fusion surgery. There has
been some literature to demonstrate the safety and efficacy of oral naloxone to decrease the
time to bowel movements after gastrointestinal surgery, to date, there have been no studies
within the spine fusion literature to investigate oral naloxone's effects on the time to
bowel movements.
The aim of the present study is to use the previously established protocols and doses
established in the gastrointestinal literature to see whether oral naloxone can decrease the
time to first bowel movements.
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