Furcation Defects Clinical Trial
Official title:
Clinical and Radiographic Outcomes of Class II Furcation Defects Management Using Propolis: A Case Series
Furcation involvement represents a challenge for treatment to many periodontists due to many factors including access, morphology, and variations of anatomical features of the furcation area. Furcation involvement treatment includes non-surgical periodontal therapy, resective surgery and regenerative surgery, regenerative therapy utilizing different graft materials and membranes is of high cost and research for new materials that can be cost-effective and available for all patients is continuing, propolis have been shown to be cost-effective therapy for bone and wound healing.
Propolis is a natural resinous product of the bee workers collected from trees to use it to stick their hives and form a coat to protect their hives from all sources of bacteria and invasions. Propolis is composed of more than 300 compounds, the most important of them are flavonoids like CAPE (caffeic acid phenyl ester). Propolis have shown anti-inflammatory, anti-oxidant, anti-bacterial, anti-fungal, anti-viral and more importantly regenerative effect and bone formation capabilities. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT04851548 -
Evaluate the Effect of Hyaluronic Acid in the Treatment of Furcation Involvement
|
N/A | |
| Completed |
NCT03207698 -
PRF+1% MF for Class II Mandibular Furcation Defects
|
Phase 2/Phase 3 | |
| Recruiting |
NCT06025955 -
Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.
|
N/A | |
| Not yet recruiting |
NCT05721313 -
Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary Study
|
N/A | |
| Not yet recruiting |
NCT05481580 -
Restorations and Furcation Involvement on Molars
|
||
| Recruiting |
NCT05541614 -
Flapless Application of Enamel Matrix Derivative in Class II Mandibular Furcation Defects
|
N/A | |
| Terminated |
NCT04059458 -
Mandibular Furcation III Regeneration (FURC-III-REGEN)
|
Phase 4 | |
| Withdrawn |
NCT03917030 -
Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade II Furcation Defects
|
N/A | |
| Terminated |
NCT04059445 -
Mandibular Furcation II Regeneration
|
Phase 4 | |
| Withdrawn |
NCT04017429 -
Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade III Furcation Defects (FURC-III-OST)
|
N/A | |
| Completed |
NCT02369250 -
Rosuvastatin Gel With 1:1 Mixture of Platelet-rich Fibrin and Bone Graft in Mandibular Degree II Furcation Defects
|
Phase 4 | |
| Not yet recruiting |
NCT06116487 -
MRI as Alternative to CBCT for the Assessment of Furcation Involvement in Molars
|
||
| Completed |
NCT03578744 -
Comparison of Platelet Rich Fibrin as Graft & Membrane Vs Hyaluronic Acid & Amniotic Membrane in the Treatment of Interradicular Defects
|
N/A | |
| Recruiting |
NCT03180658 -
Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans
|
N/A | |
| Active, not recruiting |
NCT05259982 -
Vital Root-resective Therapy in Furcation-involved Maxillary Molars
|
N/A | |
| Active, not recruiting |
NCT02132806 -
Piezosurgery in the Treatment of Class II Furcation Involvement
|
N/A | |
| Completed |
NCT02102360 -
Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial.
|
Phase 4 | |
| Not yet recruiting |
NCT06270303 -
Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects
|
N/A | |
| Completed |
NCT03354182 -
Surgical Treatment of Mandibular Furcations Using a Xenograft With/Without a Collagen Membrane
|
N/A | |
| Completed |
NCT04842188 -
Furcation Treatment With L-PRF and aPDT
|
N/A |