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Clinical Trial Summary

Furcation involvement represents a challenge for treatment to many periodontists due to many factors including access, morphology, and variations of anatomical features of the furcation area. Furcation involvement treatment includes non-surgical periodontal therapy, resective surgery and regenerative surgery, regenerative therapy utilizing different graft materials and membranes is of high cost and research for new materials that can be cost-effective and available for all patients is continuing, propolis have been shown to be cost-effective therapy for bone and wound healing.


Clinical Trial Description

Propolis is a natural resinous product of the bee workers collected from trees to use it to stick their hives and form a coat to protect their hives from all sources of bacteria and invasions. Propolis is composed of more than 300 compounds, the most important of them are flavonoids like CAPE (caffeic acid phenyl ester). Propolis have shown anti-inflammatory, anti-oxidant, anti-bacterial, anti-fungal, anti-viral and more importantly regenerative effect and bone formation capabilities. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06060340
Study type Interventional
Source Cairo University
Contact Ahmed Said Allam, BDs
Phone 01093929125
Email ahmed.allam@dentistry.cu.edu.eg
Status Recruiting
Phase Early Phase 1
Start date October 15, 2023
Completion date October 15, 2024

See also
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Not yet recruiting NCT06116487 - MRI as Alternative to CBCT for the Assessment of Furcation Involvement in Molars
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Recruiting NCT03180658 - Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans N/A
Active, not recruiting NCT05259982 - Vital Root-resective Therapy in Furcation-involved Maxillary Molars N/A
Active, not recruiting NCT02132806 - Piezosurgery in the Treatment of Class II Furcation Involvement N/A
Completed NCT02102360 - Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial. Phase 4
Not yet recruiting NCT06270303 - Use of a Bone Substitute Material in the Surgical Therapy of Furcation Defects N/A
Completed NCT03354182 - Surgical Treatment of Mandibular Furcations Using a Xenograft With/Without a Collagen Membrane N/A
Completed NCT04842188 - Furcation Treatment With L-PRF and aPDT N/A