Furcation Defects Clinical Trial
Official title:
Evaluate the Effectiveness of Bioactive Hyaluronic Acid in the Treatment of Furcation Involvement
the effect Hyaluronic Acid in the Treatment of Furcation Involvement
Status | Not yet recruiting |
Enrollment | 18 |
Est. completion date | September 20, 2022 |
Est. primary completion date | September 20, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 55 Years |
Eligibility | Inclusion Criteria: 1. Selected teeth: Permanent first and second molars in the mandible. 2. Furcation dimension: Radiographic and clinical evidence of exhibiting defects due to Grade II furcation with at least 2 millimeters probing depth horizontally and at least 5 millimeters probing depth circumferential. 3. Gender: both males and females. 4. Age range: between 18 and 55 years. 5. Health status: healthy patients non-systemic diseased except controlled diabetic. 6. Compliance: Patients will be willing and able to comply with adequate oral hygiene protocols. Exclusion Criteria: 1. Patients that received periodontal regenerative therapy within the past 12 months. 2. Patients that are lactating. 3. Pregnant patients. 4. Smokers. 5. Patients with pulp infection. 6. Patients with trauma resulting from occlusion. 7. Patients with receding gum. 8. Patients with tooth mobility greater than grade II. 9. Patients that will not comply with the hygiene protocols in Phase I therapy. 10. Patients with potential illnesses that can influence the periodontal therapy outcomes. 11. Patients that are taking medications that can interfere with the healing outcomes of the periodontal wound. 12. Patients allergic to any drugs. |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Riyadh Elm University |
Ainamo J, Bay I. Problems and proposals for recording gingivitis and plaque. Int Dent J. 1975 Dec;25(4):229-35. — View Citation
Björn H, Halling A, Thyberg H. Radiographic assessment of marginal bone loss. Odontol Revy. 1969;20(2):165-79. — View Citation
Carranza, F. A. & Newman, M. G., 2018. Clinical Periodontology. USA: WB Saunders & Co.
Gaurav Bakutra., et al. "Prevalence, Extension and Severity Associated Risk Factors Associated with Furcation Involvement in an Adult Population. An Epidemiological Study
Glickman, I. (1972). Clinical Periodontology: Prevention, Diagnosis, and Treatment of Periodontal Disease in the Practice of General Dentistry (4th ed.). Saunder.
https://doi.org/10.1902/jop.1959.30.1.7
Kalra SH, Monga C, Kalra KH, Kalra SH. A roentgenographic assessment of regenerative efficacy of bioactive Gengigel(®) in conjunction with amnion membrane in grade II furcation defect. Contemp Clin Dent. 2015 Apr-Jun;6(2):277-80. doi: 10.4103/0976-237X.156068. — View Citation
Pilloni A, Rojas MA. Furcation Involvement Classification: A Comprehensive Review and a New System Proposal. Dent J (Basel). 2018 Jul 23;6(3). pii: E34. doi: 10.3390/dj6030034. Review. — View Citation
Sahayata VN, Bhavsar NV, Brahmbhatt NA. An evaluation of 0.2% hyaluronic acid gel (Gengigel ®) in the treatment of gingivitis: a clinical & microbiological study. Oral Health Dent Manag. 2014 Sep;13(3):779-85. — View Citation
Sakpal TV. Sample size estimation in clinical trial. Perspect Clin Res. 2010 Apr;1(2):67-9. — View Citation
Sandhu GK, Khinda PK, Gill AS, Kalra HS. Surgical re-entry evaluation of regenerative efficacy of bioactive Gengigel(®) and platelet-rich fibrin in the treatment of grade II furcation: A novel approach. Contemp Clin Dent. 2015 Oct-Dec;6(4):570-3. doi: 10. — View Citation
* Note: There are 11 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | evaluate the regenerative effect of hyaluronic acid | measurement of the bone gain after the treatment with hyaluronic acid in millimeters | 6 months |
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