Furcation Defects Clinical Trial
Official title:
The Effect of Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans
Objective: To compare the effect of guided tissue regeneration (GTR) + concentrated growth factors (CGF) + bone graft and CGF + bone graft in the treat of II° furcations of human mandibular molars. Methods: At least thirty II°furcation involvements in mandibular molars will be included and randomly divided into two groups. The experimental group will accept GTR + CGF + bone graft therapy, and the control group will accept CGF + bone graft therapy. The clinical examination and cone beam computed tomography (CBCT) will be performed at baseline and 1 year post-surgery.
Status | Recruiting |
Enrollment | 30 |
Est. completion date | July 1, 2020 |
Est. primary completion date | May 1, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility |
Inclusion Criteria: - IIĀ° furcation involvements in mandibular molars - after periodontal therapy. Exclusion Criteria: - not healthy |
Country | Name | City | State |
---|---|---|---|
China | Peking university School and Hospital of Stomatology | Beijing | Beijing |
Lead Sponsor | Collaborator |
---|---|
Jing Qiao |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | clinical measurement | Probing depth | 1 year | |
Primary | clinical parameter | clinical attachment loss | 1 year | |
Secondary | radiographic parameter | cone beam computerized tomographic scanning | 1 year |
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