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Fungal Meningitis clinical trials

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NCT ID: NCT01802385 Completed - Clinical trials for Cryptococcal Meningitis

Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis

ASTRO-CM
Start date: March 9, 2015
Phase: Phase 3
Study type: Interventional

This is a phase III trial to determine whether adjunctive sertraline will lead to improved survival 18-week survival. There was an initial phase I/II unmasked dose finding pharmacokinetic study of CSF concentrations in 172 persons conducted from August 2013 to August 2014. See NCT03002012.