Mirtazapine Versus Placebo in Functional Dyspepsia

Status Recruiting

Clinical Trial Summary

Double-blind randomized controlled trials of 8 weeks mirtazapine 15 mg daily or placebo, followed by 8 weeks of open-label mirtazapine 15 mg daily

Clinical Trial Description

Double-blind randomized controlled trials of 8 weeks mirtazapine 15 mg or placebo, followed by 8 weeks of open-label mirtazapine

Two weeks run-in, 8 weeks randomized, 8 weeks open label

Assessments include

- dyspepsia questionnaire

- Nepean dyspepsia index

- Daily diary

- Vital signs ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01240096
Study type	Interventional
Source	Universitaire Ziekenhuizen Leuven
Contact	Jan Tack, M.D., Ph.D.
Phone	+3216344225
Email	jan.tack@med.kuleuven.be
Status	Recruiting
Phase	Phase 4
Start date	September 2006
Completion date	December 2011

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04656730` - Effect of STW5 (Iberogast ®) and STW5-II (Iberogast N®) on Transit and Tolerance of Intestinal Gas	Phase 4
Completed	`NCT04464369` - Functional Dyspepsia: Validation of the Leuven Postprandial Distress Scale (LPDS) in a Placebo-controlled Trial	Phase 4
Completed	`NCT01671670` - Acupuncture for Patients With Function Dyspepsia	Phase 2/Phase 3
Completed	`NCT00987805` - Efficacy of Banhasasim-tang on Functional Dyspepsia	Phase 4
Completed	`NCT00693407` - Study of Endogenous Inhibitory Modulation During Gastric and Somatic Stimulation	N/A
Completed	`NCT00761358` - To Verify the Efficacy of Z-338 in Subjects With Functional Dyspepsia	Phase 3
Recruiting	`NCT04540549` - Effects of Exercise on Functional Dyspepsia Based on Rome IV	N/A
Recruiting	`NCT03652571` - Nortriptyline for the Treatment of Functional Dyspepsia	Phase 3
Recruiting	`NCT06068114` - Gastric Pathophysiology in Diabetes
Recruiting	`NCT03825692` - International Clinical Study of Zhizhu Kuanzhong Capsule	Phase 4
Not yet recruiting	`NCT04548011` - Acupuncture of Different Treatment Frequency on Improving Quality of Life in Patients With Functional Dyspepsia	N/A
Terminated	`NCT02567578` - A Trial to Evaluate the Efficacy and Safety of YH12852 in Patients With Functional Dyspepsia	Phase 2
Completed	`NCT03007433` - Assessment of GI Function to a Large Test Meal by Non-invasive Imaging	N/A
Active, not recruiting	`NCT00990405` - Clinical Study to Evaluate the Efficacy and the Safety of Eradication Therapy for Helicobacter Pylori in Functional Dyspepsia	Phase 4
Completed	`NCT00404534` - Helicobacter Eradication Relief of Dyspeptic Symptoms	Phase 3
Completed	`NCT03043625` - Visceral Manipulation Treatment to Patients With Non-specific Neck Pain With Functional Dyspepsia	N/A
Completed	`NCT03225248` - Efficacy and Safety of UI05MSP015CT in Functional Dyspepsia	Phase 3
Recruiting	`NCT05587127` - Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia	N/A
Recruiting	`NCT01021475` - Does Visceral Manipulation Works in Treating Functional Dyspepsia?	Phase 1
Completed	`NCT00599677` - Randomized Controlled Trial of Acupuncture for Functional Dyspepsia	N/A