Clinical Trials Logo
  1. Home
  2. Functional Abdominal Pain
  3. NCT01675050

A Placebo-controlled Crossover Trial Using Cyproheptadine To Treat Children With Functional Abdominal Pain

Functional Abdominal Pain Clinical Trial

Official title:
A Placebo-controlled Crossover Trial Using Cyproheptadine To Treat Children With Functional Abdominal Pain

Clinical Trial Summary

The investigators hypothesize that using Cyproheptadine in a placebo-controlled crossover trial would help relieve abdominal pain associated with FAP in children, achieving a greater response than that observed with placebo. In addition to assessing self-report of pain and other symptoms, the investigators also propose to perform experimental somatic pain testing to determine if there is evidence of peripherally-maintained central sensitization in children with FAP. The investigators also hypothesize that there will be an increase in somatic pain threshold after completion of a Cyproheptadine course compared to baseline testing prior to treatment, and compared to placebo. This would allow children with FAP to return to normal function, improve symptoms and overall general well-being

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01675050
Study type Interventional
Source University of Michigan
Contact Emilia Mondragon
Email emondrag@med.umich.edu
Status Recruiting
Phase Phase 2
Start date August 2012
Completion date August 2013
View Details
See also
  Status Clinical Trial Phase
Completed NCT03558009 - Epidemiological Analysis for Hereditary Angioedema Disease
Completed NCT03252743 - ICBT for Pain-predominant FGIDs in Children and Adolescents: an Implementation Study. N/A
Active, not recruiting NCT02075437 - Feeling and Body Investigators N/A
Completed NCT03901560 - Music Therapy: Sickle Cell and Pain Crisis
Completed NCT02389998 - Efficacy of Open Label Placebo in Children With FGIDs N/A
Withdrawn NCT01269671 - Efficacy of Combination Therapy vs Placebo for Pediatric Functional Abdominal Pain Phase 1
Recruiting NCT03823742 - Do Biomarkers Predict Response to a Pediatric Chronic Pain Symptom Management Program? N/A
Completed NCT01118988 - Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents N/A
Completed NCT00876291 - Efficacy of Lactobacillus GG (LGG) in Children With Abdominal Pain N/A
Completed NCT04922476 - Effect of 35624® Alflorex® in Functional Gastrointestinal Disorders (FGIDs) in Children. N/A
Active, not recruiting NCT02920268 - Just in TIME - Intervention With Dance and Yoga for Girls With Recurrent Abdominal Pain N/A
Completed NCT02113605 - Cognitive Behavior Therapy (CBT) for Children With Functional Gastrointestinal Disorders N/A
Completed NCT02872961 - SIBO, Immune Activation, and FGIDs in Children
Completed NCT00327548 - Use of Guided Imagery for Functional Abdominal Pain in Children: Phase 3