Descemet Endothelial Thickness Comparison Trial I — DETECT I  

Fuchs Clinical Trial

Official title: Descemet Endothelial Thickness Comparison Trials (DETECT I & II)

Status Recruiting

Clinical Trial Summary

Descemet Endothelial Thickness Comparison Trial (DETECT) I is a multi-center, outcome assessor-masked, placebo-controlled clinical trial randomizing 160 patients in a 2x2 factorial design. The purpose of this study is to determine differences in visual outcomes between two types of corneal transplant surgeries, ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK) and Descemet membrane endothelial keratoplasty (DMEK), and to determine the effect of rho-kinase inhibitors on endothelial cell loss.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Fuchs

• NCT number: NCT05289661
• Study type: Interventional
• Source: Stanford University
• Contact: Nicole Varnado, MPH
• Phone: 650-725-1688
• Email: nvarnado@stanford.edu
• Status: Recruiting
• Phase: Phase 3
• Start date: July 15, 2022
• Completion date: March 31, 2027