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Supine Positioning for Graft Attachment After Descemet Membrane Endothelial Keratoplasty — SUPER-DMEK  

Fuchs' Endothelial Dystrophy Clinical Trial

Official title:
Supine Positioning for Graft Attachment After Descemet Membrane Endothelial Keratoplasty: a Randomized Controlled Trial

Clinical Trial Summary

This randomized controlled trial evaluates the efficacy and safety of postoperative supine head positioning on graft attachment after Descemet membrane endothelial keratoplasty in patients with Fuchs' endothelial corneal dystrophy (FECD).

Clinical Trial Description

In Descemet membrane endothelial keratoplasty (DMEK), an air or gas bubble is inserted in the anterior chamber of the eye to keep the ultrathin endothelial corneal graft attached to the patients own cornea. Supine positioning is thought to improve attachment by using the tamponade effect of the bubble. At present, it is unclear how long supine positioning is required. Positioning regimens vary between one hour to over one week. In this trial, the investigators will assess if prolonged supine positioning for 5 days improves graft attachment and long-term outcomes compared to supine positioning for 1 day. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05399095
Study type Interventional
Source University Eye Hospital, Freiburg
Contact
Status Completed
Phase N/A
Start date May 23, 2022
Completion date May 23, 2023
View Details
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