Trial of Netarsudil for Acceleration of Corneal Endothelial Restoration

Status Terminated

Clinical Trial Summary

Subjects with Fuchs dystrophy will be randomized to use either netarsudil or placebo eye drops to determine if the use of netarsudil accelerates migration of host peripheral corneal endothelial cells to restore the central endothelial cell layer.

Clinical Trial Description

Subjects with Fuchs endothelial dystrophy will have the central corneal endothelium and guttae-covered Descemet membrane surgically removed. Subjects will be randomized to use netarsudil or placebo eye drops once daily. Visual acuity, corneal clearing and central endothelial cell density will be monitored for the 3-month study duration. ;

Study Design

Related Conditions & MeSH terms

Fuchs' Endothelial Dystrophy

Clinical Trial Details

NCT number	NCT03971357
Study type	Interventional
Source	Price Vision Group
Contact
Status	Terminated
Phase	Phase 2/Phase 3
Start date	July 22, 2019
Completion date	August 26, 2021

View Details

See also
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