Glanatec(R) for Descemet Stripping in Fuch's Endothelial Dystrophy

Status Recruiting

Clinical Trial Summary

In brief, the objective of this study is to investigate whether the drug Glanatec ® which is approved in Japan for glaucoma and ocular hypertension, can be used in patients with Fuchs endothelial dystrophy who have had a descemet stripping procedure without endothelial keratoplasty. While some limited data exists as a proof of concept in in vitro or animal studies, and Glanatec® has been successfully used in a recently published case series for this indication, there is insufficient data to show that this drug can be effectively used for corneal cell clearing while maintaining patient safety. The goal of the study is to provide sufficient proof of concept for the use of this drug in patients with FED whose only treatment alternative is to undergo corneal transplant.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Fuchs' Endothelial Dystrophy

Clinical Trial Details

NCT number	NCT03249337
Study type	Interventional
Source	NorthShore University HealthSystem
Contact	Duanny Alva, MPH
Phone	847-570-1783
Email	dalva@northshore.org
Status	Recruiting
Phase	Phase 4
Start date	December 6, 2017
Completion date	December 2021

View Details

See also
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