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Clinical Trial Summary

To test the variability of specific ribonucleic acid (RNA) and proteins as well as frataxin levels in samples of blood and buccal cells taken directly from patients with Friedreich's ataxia (FRDA) in order to confirm potential new biomarkers of disease in patients with FRDA.


Clinical Trial Description

Primary Objective:

The primary objective of this study is to identify whether frataxin levels and specific RNAs and proteins in blood and buccal cells differ between patients with FRDA and controls.

Secondary Objective:

The secondary objectives of this study are:

- To understand the variability of frataxin and specific RNAs and proteins identified in buccal cells.

- To correlate levels of frataxin and specific RNAs and proteins with features of FRDA.

- To correlate levels of frataxin and specific RNAs and proteins with triglycerides, high density lipoprotein (HDL), low density lipoprotein (LDL) levels, and other lipids. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04255680
Study type Observational
Source Larimar Therapeutics, Inc.
Contact
Status Completed
Phase
Start date January 14, 2020
Completion date June 30, 2020

See also
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