PVI Based Intraoperative Fluid Management in Head and Neck Free Flap Reconstructive Surgeries

Free Tissue Flaps Clinical Trial

Official title: Pleth Variability Index Based Intraoperative Fluid Management in Head and Neck Free Flap Reconstructive Surgeries

Status Completed

Clinical Trial Summary

Intraoperative fluid given according to BMI in group B and according to pulse oximeter- derived pleth variability index(MASIMO RAINBOW PULSE CO OXIMETRY) in group G. Comparison of haemodynamics, urine output,blood lactate levels, blood sugar, flap sugar and coagulation profile between the two groups.

Clinical Trial Description

A sample size of 80 taken and computer generated random allocation done to divide the patients in two groups(40 each). Head and neck onco surgery patients undergoing resection and reconstruction with radial artery free flap and antero lateral thigh free flap of duration 4-6 hours taken for surgery.

Group B to receive intravenous fluid according to body weight stating at the rate 6-8 ml/kg/hr.

Group G to receive intravenous fluid according to Pleth variability index value(4-11).Blood loss up to 10% replacement by colloids.

Comparison of following parameters:

Demography, haemodynamics,urine output .blood lactate, ph, oxygenation index ,thromboelastography (TEG), blood sugar, flap sugar . ;

Related Conditions & MeSH terms

• Free Tissue Flaps

• NCT number: NCT03116178
• Study type: Interventional
• Source: Rajiv Gandhi Cancer Institute & Research Center, India
• Status: Completed
• Phase: N/A
• Start date: March 2016
• Completion date: October 2016