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Frailty in Liver Transplant Exercise (FLEX) Trial — FLEX  

Frailty Clinical Trial

Official title:
Frailty in Liver Transplant Exercise (FLEX) Trial

Clinical Trial Summary

Frailty is common in patients with end-stage liver disease. It's characterized by reduced strength, low endurance and reduced physical function. While exercise intervention can improve frailty in geriatric patients without liver disease, whether or not exercise intervention can improve frailty in liver transplant candidates remains unknown.

Clinical Trial Description

The long-term goal is to better understand how exercise impacts frailty in order to identify treatments that can improve both patient-oriented outcomes and access to liver transplantation for end-stage liver disease patients. The specific objective of this proposal is to generate pilot feasibility data required for future multicenter R01 application to the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) which will test the novel central hypothesis that exercise improves frailty and lessens waiting-list mortality. Additionally, another goal of the study is to establish an optimal frailty tool for liver transplant candidates. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04200846
Study type Interventional
Source Milton S. Hershey Medical Center
Contact
Status Withdrawn
Phase N/A
Start date July 1, 2021
Completion date December 1, 2022
View Details
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