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Clinical Trial Summary

Frailty is a geriatric syndrome leading to physical deterioration including muscle wasting (sarcopenia) and unintentional weight loss. There are currently no approved therapies for frailty. Ghrelin is a hormone produced by the stomach that stimulates appetite centers in the brain. The investigators already know that a single dose of Ghrelin improves food intake immediately after the dose in frail older people. In addition, exercise programs have been shown to improve strength and function in older people. In this study, the investigators are trying to find out if a joint intervention of ghrelin and resistance training will improve walking, balance and leg strength in frail elderly people.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT01898611
Study type Interventional
Source University of Pennsylvania
Contact
Status Completed
Phase Phase 2
Start date July 1, 2013
Completion date August 31, 2016

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