Frail Elderly Clinical Trial
Official title:
Cognitive Function and Prevalence of Amyloid Marker in Frail Older Adults
The current study seeks to examine the prevalence of amyloid pathology, among patients referred to the Toulouse Geriatric Frailty Clinic presenting objective memory impairment. We also aim to fully characterize the clinical progression of frail cognitively impaired patients presenting AD (Alzheimer Disease) pathology vs those who also present a cognitive impairment but do not have AD pathology.
The COGFRAIL study is a monocentric study integrating the longitudinal follow-up of 345 individuals referred to the Toulouse Frailty Clinic during 2 years. The procedure consists in neuroimaging to diagnose the presence of amyloid plaques in the brains and permit earlier detection of Alzheimer's disease. - Visits will be scheduled at baseline, 1 and 2 years for a full neuropsychological, functional and physical evaluation. - At 6 and 18 months patients will be seen in consultation by a Geriatrician and research assistant for a medical check. - PET-Scan will be scheduled in the 2 months following inclusion for amyloid measurements. The MRI will be proposed, depending on the clinical relevance - A blood sample for biobank will be taken at visit 2 and at the end of the study Extension study (CogFrail-Plus): The extension study will integrate an additional 2 years follow-up of the COGFRAIL study participants, following the initial 2 years period of the study: - 2 Visits will be scheduled at 36 and 48 months for a full neuropsychological, functional and physical evaluation - At 30 and 42 months patients will be seen in consultation by a Geriatrician and research assistant for a medical check - A blood sample will be taken at 36 and 48 months. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02890927 -
Geriatric-CO-mAnagement for Cardiology Patients in the Hospital
|
N/A | |
| Completed |
NCT00384709 -
Geriatric Education and Its Effect on Certain Aspects of Hospital Care of Nursing Home Patients
|
N/A | |
| Completed |
NCT05447533 -
Clostridioides Difficile and Frailty
|
N/A | |
| Completed |
NCT03722017 -
Drug Reduction in Older Patients: The DROP Trial
|
N/A | |
| Enrolling by invitation |
NCT05411393 -
Synergizing Home Health Rehabilitation Therapy
|
N/A | |
| Completed |
NCT03477097 -
Frailty Prevention Through Improvement of Nutrition Physical Activity and Social Participation
|
N/A | |
| Recruiting |
NCT02333214 -
Effectiveness of a Program Using Video Games Associated With Conventional Physiotherapy in Physical Functioning in Frail Elderly Compared to Conventional Physiotherapy
|
N/A | |
| Not yet recruiting |
NCT00756535 -
Exercise Training in a Geriatric Hospital Ward
|
N/A | |
| Completed |
NCT01829594 -
Case Managers to Frail Older People a Randomized Controlled Trial
|
N/A | |
| Recruiting |
NCT04095338 -
Innovative Models in the Rehabilitation of the Elderly With Hip Fractures Through Technological Innovation
|
N/A | |
| Completed |
NCT02975089 -
A Pilot Study Comparing Effects of Nutrients Supplements and Dietary Approach in Frailty Management
|
N/A | |
| Completed |
NCT01922167 -
Resistance Exercise Training and Amino Acid Leucine Supplementation in Frail Elderly Women
|
N/A | |
| Completed |
NCT02591602 -
Teleradiology Program for Frail Patients Living at Home or in Nursing-homes
|
N/A | |
| Completed |
NCT00105781 -
Nurse Physical Activity Counseling in Primary Care
|
N/A | |
| Completed |
NCT05802537 -
Home-Based Exergame Program for Community-Dwelling Older Adults
|
N/A | |
| Completed |
NCT03990415 -
Stay Strong, Stay Healthy Outcomes in Older Adults
|
N/A | |
| Terminated |
NCT02766075 -
A STEP for Patients Prior to Undergoing TAVR: A Pilot Study
|
N/A | |
| Completed |
NCT01607736 -
Pilot Study of Virtual Gait Training in Older Adults
|
N/A | |
| Completed |
NCT00038155 -
Rehabilitation for Older Adults From Acute Medical Conditions
|
Phase 2 | |
| Completed |
NCT04885608 -
PReGe in Outdoor Fitness Parks
|
N/A |