Fracture of Proximal Femur Clinical Trial
Official title:
Evaluation Effect of Adding Dexmedetomidine to Bupivacaine for Paravertebral Block in Femoral Fractures
Verified date | September 2020 |
Source | Mansoura University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Fracture femur is a common that results in severe pain. Many methods of regional and peripheral analgesia have been described to treat such pain. In this study the investigators consider using paravertebral block to treat post-fracture pain. Additionally, they consider adding dexmedetomidine to the used local anesthetic solution to prolong the duration of this block and hence postoperative analgesia.
Status | Completed |
Enrollment | 88 |
Est. completion date | December 1, 2015 |
Est. primary completion date | October 1, 2015 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 30 Years to 80 Years |
Eligibility |
Inclusion Criteria: - American Society of Anesthesiologists physical class I or II Exclusion Criteria: - Patient refusal. - Severe or uncompensated cardiovascular disease. - Severe or uncompensated renal disease. - Severe or uncompensated hepatic disease. - Severe or uncompensated endocrinal disease. - Pregnancy. - Postpartum ladies. - Lactating females. - Allergy to any of the study medications . - Coagulation disorders. - Infection at the site of needle insertion |
Country | Name | City | State |
---|---|---|---|
Egypt | Mansoura university | Mansoura | DK |
Lead Sponsor | Collaborator |
---|---|
Mansoura University |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Scale for radiological spread of the injectate | It will be assessed using the following scale -2; spread for two vertebral levels below the site of injection, -1; spread for one vertebral level below the site of injection, 0; stays at the level of injection, +2; spread for two vertebral levels above the site of injection, +1; spread for one vertebral level above the site of injection | for 20 min after performing the blockade | |
Secondary | Pain scores | The severity of pain will be assessed using a visual analog scale (VAS) | For 48 hours after surgery | |
Secondary | Duration of postoperative analgesia | The period from completion of the block to time of administration of the first request of rescue analgesic for postoperative pain will be recorded | for 24 hours after surgery | |
Secondary | Postoperative analgesic consumption | Total postoperative analgesic consumption | for 48 hours after surgery |