Management of Fournier Gangrene at Ibn Rochd University Hospital Center

Fournier Gangrene Clinical Trial

Official title:

Fournier's Gangrene: Seven Years of Experience in the Emergencies Service of Visceral Surgery at Ibn Rochd UHC

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04983056
• Other study ID #: FZBKSMP35
• Status: Completed
• Start date: January 1, 2010
• Est. completion date: July 2, 2021

Study information

• Verified date: July 2021
• Source: Centre Hospitalier Universitaire Ibn Rochd
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Case series with retrospective data collection of patients treated for Fournier's gangrene between January 2010 and March 2017. The main etiologies, risk factors, postoperative complications outcomes and long term follow up results were analyzed.

Description:

Eight four (84) patients were recruited. The average age of our patients was 49 years (with limits of 20 to 76), the male gender dominates our series (83.33%) with a sex ratio of 5M / 1W, the most frequently found risk factor was diabetes mellitus (37%). The most common etiology was anal abscesses (32%). The average time to consultation was 8 days (limits ranges from 3 to 30 days). All patients were admitted at a necrosis stage (100%). Anemia was identified in 85% of cases. The low platelets were noticed in 44.03% of cases. Hypoalbuminemia was found in 93% of cases. All patients (100%) benefited resuscitation initially and antibiotic therapy on their admission. They received emergency surgical debridement with a cleansing stoma. The average length of hospital stay was 13 days and complications occurred in 33% of cases. The mortality rate was 7.14%. then we conclude that Fournier's gangrene is a medico-surgical emergency with a high morbidity and mortality rate. Early diagnosis as well as antibiotic therapy and the quality of debridement save the patients.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 84
• Est. completion date: July 2, 2021
• Est. primary completion date: March 31, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 15 Years to 100 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of Fournier Gangrene

Exclusion Criteria:

• Other perineal diseases which are differential diagnosis of Fournier gangrene

Related Conditions & MeSH terms

• Fournier Gangrene
• Gangrene

Intervention

Procedure:
• Necrotesectomy associated with cleanleness stoma
Excision of all necrotised tissues after stool diversion and wound dressing using

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Sylvestre KABURA

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of patients who died for fournier gangrene	The mortality rate of patients with Fournier Gangrene after six months	Six months