Formularies Clinical Trial
Official title:
Differences Between Essential Medicines Lists in 135 Countries and the World Health Organization's Model List of Essential Medicines
The World Health Organization (WHO) has developed a model list of more than 400 medicines and
recommends that each country adapt the list to its own circumstances. More than 100 countries
have developed essential medicines lists.
Some countries have essential medicines lists that are very similar to the WHO's model list
and other countries have lists that are very different from the WHO's model list. Differences
between the WHO list and country lists could be explained by features of the country
including population demographics, disease prevalence, Gross Domestic Product (GDP), and
healthcare system organization. Other factors such as the influence of particular individuals
or organizations may also explain differences between countries.
The purpose of this project is to compare the essential medicines lists developed by
countries with the WHO's model list and to identify attributes of countries that are
associated with differences from the WHO list. Predictors such as region, population, life
expectancy, infant mortality rate, GDP per capita, health expenditure per capita, inequality,
and the corruption perception index will be considered.
Statistical analysis plan for objective 3 (relationship between the total number of
differences and country features)
Plots will be generated to show the relationships between variables. Correlation coefficients
will be calculated where appropriate. Two separate multivariate models will be fit to the
data for outcomes 2a and 2b [continuous, between 1 and 500]. A similar model will be fit the
total number of differences. The analytical method will be determined by the data and may be
liner regression.
Predictors:
Region-Categorical (6)
Population-Continuous
Life expectancy-Continuous
Infant mortality rate-Continuous
GDP per capita-Continuous
Health expenditure per capita
Inequality-Continuous
Corruption Perception Index-Continuous
;