Forearm Fracture Clinical Trial
Official title:
Non Steroidal Antiinflammatory Drugs Influence on Heal of Distal Radius Fracture
It is believed, that Non Steroidal Antiinflammatory Drug (NSAID) drugs slows bone healing,
but the knowledge is based only on animal studies, and the results are automatically raised
for the people.
Many patients with bone fracture must therefore avoid the formerly so popular and good
painkillers, although no clinical trial evidence is, that this medicine is really harmful
for patients with fractures.
The purpose of this study is to investigate whether these drugs slows bone healing, and what
the relationship is between various bone studies - DEXA scanning, biochemical bone marker
tests, radiographic controls and tissue examination of newly formed bone under a microscope.
How sensitive and specific, each of the above study methods? If they are just as sensitive,
the cheapest of them recommended as a routine investigation on suspicion of bone effects.
Furthermore, to compare the benefit (pain-relieving effect, influence on rehabilitation) of
these drugs and their possible harmful side effects (affected and delayed bone healing).
The expectation is that the study may contribute to increased knowledge about NSAIDs effect
do pain management, rehabilitation and the entire treatment process significantly easier and
safer, so that patients recover faster and return to usual activities.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment
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