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Foot Ulcer, Diabetic clinical trials

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NCT ID: NCT01082445 Completed - Clinical trials for Foot Ulcer, Diabetic

Effects of N-acetylcysteine on Diabetic Foot Oxygenation

Start date: August 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether N-acetylcysteine is effective in the treatment or prevention of the foot ulcers in diabetic patients.

NCT ID: NCT01060670 Completed - Clinical trials for Foot Ulcer, Diabetic

A Safety and Efficacy Study of INTEGRA® Dermal Regeneration Template for the Treatment of Diabetic Foot Ulcers

Start date: April 2010
Phase: N/A
Study type: Interventional

The objective of this study is to evaluate the safety and effectiveness of the INTEGRA® Dermal Regeneration Template for the treatment of diabetic foot ulcers located distal to the malleolus in subjects with diabetes mellitus, neuropathy, and without significantly compromised arterial circulation.

NCT ID: NCT01013792 Terminated - Clinical trials for Foot Ulcer, Diabetic

A Comparison of an Investigational Dressing to Tegaderm Matrix Wound Dressing in the Management of Diabetic Foot Ulcers

Start date: November 2009
Phase: N/A
Study type: Interventional

The primary objective is to: - Assess the effect of the Non-adherent study dressing to 3M Tegaderm Matrix Dressing with PHI technology on wound healing in patients with a diabetic foot ulcer. Secondary objectives are to: - Assess the adverse events that occur in subjects randomized to the investigational dressing in comparison to subjects randomized to the Tegaderm Matrix Dressing with PHI technology. - Assess the costs of using the investigational dressing compared to the Tegaderm Matrix Dressing with PHI technology. - Assess and compare the impact that these dressings have on patients' quality of life. - Assess the wound's biological response and pH to the study dressings.

NCT ID: NCT00796744 Completed - Diabetic Foot Clinical Trials

Safety and Efficacy Study of DSC127 in Treating Subjects With Diabetic Ulcers

Start date: October 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess if the experimental drug, DSC127, is safe, how well it can be tolerated, and how different doses effect the healing of the chronic foot ulcers in diabetic subjects.

NCT ID: NCT00711217 Completed - Clinical trials for Foot Ulcer, Diabetic

Evaluation of a Medical Food for Chronic Wounds

Start date: June 2008
Phase: Phase 3
Study type: Interventional

The study objective is to compare outcomes in subjects with a diabetic foot ulcer after 16 weeks of consuming a medical food versus a calorically similar control drink.

NCT ID: NCT00516958 Completed - Clinical trials for Foot Ulcer, Diabetic

Pilot Study of the Safety and Clinical Efficacy of Topical Dermacyn™ Wound Care to Treat Mild Diabetic Foot Infections

Start date: May 2007
Phase: Phase 2
Study type: Interventional

To compare the rates of clinical success of Topical Dermacyn™ vs. Oral Levofloxacin vs. Combined therapy, in subjects with mild diabetic foot infections in non-ischemic ulcers.

NCT ID: NCT00448903 Completed - Clinical trials for Foot Ulcer, Diabetic

Clinical Trial to Evaluate the Efficacy and Safety of Sodium Bemiparin for Treatment of Diabetic Foot Ulcers

Start date: March 2007
Phase: Phase 3
Study type: Interventional

Chronic foot ulcers are a common, severe and expensive complication in patients with diabetes and often causes lower-extremity amputation. The aim of this study is to evaluate the effect of bemiparin as treatment of diabetic foot ulcers.

NCT ID: NCT00399425 Terminated - Clinical trials for Foot Ulcer, Diabetic

Efficacy of a Low-Molecular-Weight Heparin (Bemiparin) in the Treatment of Chronic Foot Ulcers in Diabetic Patients

Start date: June 2001
Phase: Phase 2/Phase 3
Study type: Interventional

To assess the efficacy of bemiparin (low molecular weight heparin) for 3 months in the treatment of chronic foot ulcers in diabetic patients.

NCT ID: NCT00351767 Completed - Clinical trials for Foot Ulcer, Diabetic

A Study to Assess the Effect of Topical Recombinant Human Vascular Endothelial Growth Factor for Induction of Healing of Diabetic Foot Ulcers

Start date: January 2006
Phase: Phase 2
Study type: Interventional

This is a Phase II, double-blind, randomized, placebo-controlled study to evaluate the safety and efficacy of three different doses of topically applied telbermin in subjects ≥ 18 years old with diabetic foot ulcers. Approximately 160 adult subjects with Type 1 or Type 2 diabetes mellitus will be enrolled at approximately 40 investigational sites in the United States and Canada.

NCT ID: NCT00318214 Terminated - Clinical trials for Diabetes Complications

Safety and Efficacy Study of MRE0094 to Treat Large, Single or Multiple, Chronic, Neuropathic, Diabetic Foot Ulcers

Start date: June 2006
Phase: Phase 2
Study type: Interventional

This is a clinical research study of an experimental topical drug for the treatment of chronic, neuropathic, diabetic foot ulcers. The purpose of the study is to determine the safety of the experimental drug when applied to large, diabetic foot ulcers. The study will also determine if the experimental drug can safely promote healing of diabetic foot ulcers better than standard treatments currently available to doctors. Patients participating in the study may receive an active drug (MRE0094) or inactive drug (placebo). What treatment a patient will receive is determined by chance (like drawing a number from a hat). All patients will receive additional care for diabetic foot ulcers during the study. Participation in the study can be up to 4½ months.