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Clinical Trial Summary

Rebound pain after surgeries under peripheral nerve block is defined as the appearance of severe acute postoperative pain after regression of the sensory block. The incidence of this condition can reach up to 40-50% in patients undergoing ambulatory surgeries. Rebound pain represents a clinically significant issue that may outweigh the benefits of regional anaesthesia. This is particularly significant for painful outpatient surgeries, where inadequately managed pain can result in distress, potentially affecting patient satisfaction and recovery. It may also lead to unplanned utilization of healthcare resources or readmissions. Orthopaedic foot surgery is a prevalent outpatient surgery, potentially painful, where rebound may be a difficult challenge. However, to date, prospective studies focusing specifically on rebound pain in outpatient foot surgery are limited. Identifying conditions associated with rebound pain or at-risk patients could facilitate the development of preventive and treatment strategies, thereby enhancing pain management or relief. Younger age, female sex and bone surgery are non-modifiable factors associated with severe rebound pain. Perioperative intravenous dexamethasone has been identified as a modifiable independent risk factor associated with a reduced incidence of rebound pain. Regarding anaesthetic factors, the duration of the peripheral block has been proposed as a potentially modifiable factor influencing rebound pain; however, current evidence does not support this hypothesis. The goal of this prospective observational study is to evaluate the incidence of rebound pain specifically in outpatient orthopaedic foot surgery involving bone under popliteal sciatic nerve block and to assess the possible association between sensory block duration and the incidence of rebound pain.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06309381
Study type Observational
Source Hospital Universitario Doctor Peset
Contact Javier Barrio, MD, PhD
Phone 0034646819882
Email jbarrio.ma@gmail.com
Status Recruiting
Phase
Start date February 8, 2023
Completion date October 2024

See also
  Status Clinical Trial Phase
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Terminated NCT05354791 - Pre-post Spinal Popliteal Block
Terminated NCT01325012 - Ultrasound-Guided Continuous Sciatic Nerve Blocks: Popliteal Versus Subgluteal Catheters Phase 4
Enrolling by invitation NCT05425979 - Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks Phase 4
Terminated NCT01615939 - A Study Comparing Continuous Sciatic Nerve Block to Single Shot Sciatic Nerve Block Phase 4
Enrolling by invitation NCT06465992 - Liposomal Bupivacaine With Dexamethasone for Foot Surgery Phase 4
Completed NCT05368012 - MIDCAB (Mid-Calf Block) for Foot Surgery Phase 4
Enrolling by invitation NCT04575688 - Periarticular Injection Versus Popliteal Block Phase 4
Recruiting NCT01546077 - Placement of Perineural Catheters in the Popliteal Region Phase 4
Completed NCT04134962 - Evaluation of a New Tool for Measuring Hindfoot Alignment Under Load and in 3D.
Enrolling by invitation NCT04872322 - Effect of Ropivacaine During Popliteal Nerve Block in Foot and Ankle Surgery Phase 3