Food Habits Clinical Trial
Official title:
Comparison of Microbiota and Quality of Life for a Low FODMAPs Versus Standard Dietary Advice in Patients With Irritable Bowel Syndrome
IBS is a global disease, patients often because of long-term symptoms of recurrent, not timely diagnosis and treatment effect is not ideal and frequent treatment, seriously affect the quality of life, and cause the corresponding economic and social burden.At present，a number of studies suggest that fermentable oligosaccharides, disaccharides and monosaccharides and polyols (FODMAPs) can induce IBS symptoms.Data from large randomized controlled trials are limited, leaving clinicians with the challenge of providing patients with reliable guidance based on minimal evidence.
IBS is a global disease, patients often because of long-term symptoms of recurrent, not
timely diagnosis and treatment effect is not ideal and frequent treatment, seriously affect
the quality of life, and cause the corresponding economic and social burden.At present，a
number of studies suggest that fermentable oligosaccharides, disaccharides and
monosaccharides and polyols (FODMAPs) can induce IBS symptoms.Data from large randomized
controlled trials are limited, leaving clinicians with the challenge of providing patients
with reliable guidance based on minimal evidence.
This study will compare the effect of low FODMAPs diet and usual diet instruction on
Intestinal flora, intestinal short chain fatty acids and quality of life by two groups.The
results will answer the effect and long-term safety of Low FODMAPs diet.
;
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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