Efficacy of Lyophilized Food Extracts for Skin Prick Tests and Atopy Patch Test at Different Storage Time

Food Allergy Clinical Trial

Official title:

Comparison of Skin Prick Tests and Atopy Patch Test Results of Lyophilized Food Extracts at Different Storage Time (0, 3 and 6 Months) After Preparation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03645629
• Other study ID #: 619/2556 (EC 3)
• Status: Completed
• Phase: N/A
• Start date: January 1, 2018
• Est. completion date: July 31, 2019

Study information

• Verified date: August 2019
• Source: Mahidol University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Comparison the result of skin prick tests and atopy patch test of lyophilized food extracts at different storage time (0, 3 and 6 months) after preparation

Description:

Skin prick test were performed with lyophilized food extracts (cow milk, egg white, egg yolk, wheat, soy and shrimp) at different storage time (0, 3 and 6 months) after preparation.

Atopy patch test were performed with lyophilized food extracts (cow milk, egg white, egg yolk, wheat, soy and shrimp) at different storage time (0, 3 and 6 months) after preparation

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: July 31, 2019
• Est. primary completion date: June 30, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 3 Years to 18 Years

Eligibility

Inclusion Criteria:

• mild to moderately severe food allergy patients

• At least positive skin test to one kind of common food (commercial extract)

• Stop antihistamine or corticosteroid (if more than 20mg/day) for at least 7 days

Exclusion Criteria:

• Dermographism

• Severe systemic disease such as autoimmune disease, immune deficiency, malignancy

• Severe dermatitis or large area involment

• pregnancy

Related Conditions & MeSH terms

• Food Allergy
• Food Hypersensitivity

Intervention

Diagnostic Test:
• skin test with food at different storage times
Perform skin tests to each foods at 0, 3, 6 months after preparation and compare the results

Locations

Country	Name	City	State
Thailand	Siriraj Hospital. Mahidol University	Bangkok

Sponsors (1)

Lead Sponsor	Collaborator
Mahidol University

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	skin test result of lyophilized foods at 6 months after preparation	Perform skin prick test and atopy patch test the patients with lyophilized foods at 0, 3 and 6 months after preparation and compare the results at 6 months to 0 and 3 months.	6 month