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The Basophil Activation Test as a Diagnostic Tool in Pediatric Food Allergy

FOOD ALLERGY Clinical Trial

Official title:
Evaluation of Technical and Predictive Value of the Basophil Activation Test for Food Allergy Diagnosis in Children

Clinical Trial Summary

Background: The need for an oral food challenge (OFC) surrogate is growing in line with the continuous increase in the prevalence and severity of paediatric food allergy. The basophil activation test (BAT) has recently been reported as a promising tool for predicting the outcome of OFC in children.

Objective: We make the hypothesis that BAT might improve the sensitivity of food allergy diagnosis and spare part of current OFC in paediatric patients attending allergy departments in Marseille APHM University hospitals.

Methods: BAT will be performed in parallel with OFC in 100 paediatric patients receiving OFC during a diagnostic or follow-up procedure.

Expected results: Good concordance of BAT and OFC results leading to potential OFC replacement by BAT in at least 50% of the study population

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03265262
Study type Interventional
Source Assistance Publique Hopitaux De Marseille
Contact Ania CARSIN
Phone 04.91.68.67.65
Email ania.carsin@ap-hm.fr
Status Recruiting
Phase N/A
Start date September 1, 2017
Completion date August 1, 2020
View Details
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