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NCT03151252 Clinical Trial

Improvement of Foodallergy Diagnostic in Gastrointestinal Tract

Food Allergy Clinical Trial

Official title:
Improvement of Foodallergy Diagnostic in Gastrointestinal Tract With a New Kind of Sampling

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT03151252
Other study ID # Foodallergy in Colon
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date October 2014
Est. completion date December 2022

Study information
Verified date September 2021
Source University of Erlangen-Nürnberg Medical School
Contact Yurdaguel Zopf, Prof
Email yurdaguel.zopf@uk-erlangen.de
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Currently, diagnostic possibilities for the detection of food allergy in the gastrointestinal tract are scarce. The endoscopic segmental Lavage is the method of choice, but it´s controversial. Additional to the endoscopic segmental lavage fluid a cytobrush is used for collecting the mucosa cells and biopsies are taken. Comparative to the Lavage specific IgE antibodies, Tumor necrosis factor- alpha, Eosinophilic cation protein and mastcell tryptase were measured.

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date December 2022
Est. primary completion date December 2022
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - all patients with suspicion of food intolerance and confirmed food allergy Exclusion Criteria: - pregnant and patients under allergy medication (antihistaminic, cortison)

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Cytobrush
During the endoscopic Investigation the mucosa cells were collected by brushing the colon via cytobrush.

Locations
Country Name City State
Germany Department of Medicine 1, Hector Center for Nutrition, Exercise and Sports, Friedrich-Alexander-University Erlangen-Nuremberg Erlangen

Sponsors (1)
Lead Sponsor Collaborator
University of Erlangen-Nürnberg Medical School

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary detection of specific IgE Antibodies in colon 1 hour
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