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iFAAM: The Impact of Proton-pump Inhibitors (Antacids) on Threshold Dose Distributions — iFAAM-PPI  

Food Allergy Clinical Trial

Official title:
Integrated Approaches to Food Allergen and Allergy Risk Management: iFAAM: The Impact of Proton-pump Inhibitors (Antacids) on Threshold Dose Distributions

Clinical Trial Summary

In patients with a walnut allergy double blind placebo controlled food challenge with walnut will be combined with the intake of proton pump inhibitor (PPI) or with placebo to assess the impact of PPI on threshold level and on clinical manifestation.

Clinical Trial Description

1. detailed case history, blood sampling and prick testing with different foods will performed.

2. double blind food provocation with with three meals containing either placebo or walnut in walnut allergic patients will be performed.

3. the provocation will be combined with the intake of drug (omeprazole) or placebo (mannitol) blinded in capsules. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02552537
Study type Interventional
Source University of Zurich
Contact
Status Completed
Phase Phase 4
Start date September 2015
Completion date March 2017
View Details
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