Differentiated Thyroid Cancer Clinical Trial
Official title:
Sutent Adjunctive Treatment of Differentiated Thyroid Cancer
This study is comparing a drug called Sutent with standard of care treatment for people with
advanced thyroid cancer. Because advanced thyroid cancer is becoming increasingly common and
effective treatment options are limited, new therapies are desperately needed.
This study is designed to see if Sutent following therapy with radioactive iodine will target
cancer cells and delay disease progression better than standard therapy alone. Newly
diagnosed patients, who are scheduled to receive radioactive iodine as part of their standard
care are possible candidates. By entering into this study, participants agree to take oral
Sutent for approximately two years after completing standard therapy. During this time, study
participants will be followed closely by their doctor.
This is a two-stage, phase II, single center, targeted therapy trial enrolling patients with stage 2 (for patients younger than 45 years of age), 3 or 4 differentiated thyroid cancer. The primary objective is to assess progression free survival in this population. Sutent will be given orally at 37.5mg daily for two (2) year, or 26 cycles. Each treatment cycle will consist of 28 days. Upon treatment discontinuation, patients will be followed for survival. The frequency and type of survival follow-up assessments performed will be at the discretion of the treating physician. ;
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