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Feasibility of Slow Continuous UltraFiltration For Deresuscitation in Critically Ill Patients — SCUFFD  

Fluid Overload Clinical Trial

Official title:
Feasibility of Slow Continuous Ultrafiltration With Regional Anticoagulation for Deresuscitation in Critically Ill Patients Though Standard Central or Peripheral Venous Access.

Clinical Trial Summary

To determine the feasibility and safety of deresuscitation using slow continuous ultrafiltration with regional citrate anticoagulation and peripheral or standard central venous access.

Clinical Trial Description

Fluid deresuscitation has been shown to have favourable outcomes in the management of the critically ill patient. Whilst diuretic medications have previously been the mainstay of achieving this deresuscitation, the metabolic and biochemical complications associated with their use can limit their application. Mechanical ultrafiltration is another means of achieving fluid deresuscitation and has theoretical benefits over the use of intravenous diuretics. It allows a more titratable process, without the potential metabolic complications. The use of ultrafiltration has been limited by the requirement of wide bore central venous access. The SCUFFD study is a means of assessing whether ultrafiltration with regional anticoagulation can be achieved through standard central or peripheral venous access. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05431491
Study type Interventional
Source Belfast Health and Social Care Trust
Contact Neil Cody, MBChB
Phone 00447525261112
Email neil.cody@nhs.net
Status Recruiting
Phase N/A
Start date August 12, 2022
Completion date March 1, 2024
View Details
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