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Impact of Rational Control of Fluid Balance in the Intensive Care Unit — IRIHS-REA  

Fluid Overload Clinical Trial

Official title:
Impact of Rational Control of Fluid Balance in the Intensive Care Unit.IRIHS-REA

Clinical Trial Summary

Patients admitted in the Intensive Care Unit (ICU) frequently display and excessive fluid balance over a very short period of time. This positive fluid balance is the consequence of different organ failures (pulmonary, cardio-vascular, kidney…) or aggressive fluid resuscitation, which is mandatory in the early phase of ICU course. However recent data strongly suggest that an excessive fluid balance could be detrimental per se (increase of ICU morbidity or even mortality). There are controversies regarding the potential benefit of controlling this fluid balance with diuretics which are commonly used worldwide in various indications (acute and chronic heart failure, chronic kidney failure). In the ICU literature data are lacking, regarding the possible advantages and drawbacks of diuretics in this indication. The aim of our study is to test an algorithm with furosemide to reduce fluid overload in severe ICU-patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02345681
Study type Interventional
Source Nantes University Hospital
Contact
Status Completed
Phase Phase 3
Start date May 2015
Completion date April 2019
View Details
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