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Fluid Management clinical trials

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NCT ID: NCT05361252 Completed - Fluid Management Clinical Trials

Stroke Volume Variation-guided Fluid Infusion in Major Liver Tumour Resection

Start date: February 1, 2017
Phase: N/A
Study type: Interventional

Studies have demonstrated that the rate of change in stroke volume variation (SVV) can be used to determine the volume of body fluids during major abdominal surgery. Anaesthesiologists can use SVV as a guide for the appropriate administration of intraoperative fluids to improve postoperative prognoses. Liver surgery is a major abdominal operation, and the amount of blood lost is typically higher than that during other general abdominal surgeries. Blood loss is positively correlated with the intraoperative fluid infusion volume, and greater blood loss is associated with more postoperative complications. Additionally, comorbid liver disease or cirrhosis can increase the complexity of liver tumour resection, causing difficulty in assessing intravascular volume and determining the appropriate intraoperative infusion volume.

NCT ID: NCT05187273 Completed - Fluid Management Clinical Trials

Hemodynamic Optimization Based on a Dynamic Elastance Protocol

Start date: February 25, 2021
Phase: N/A
Study type: Interventional

In this study investigators explore the effects of a dynamic elastance guided protocol compared to a stroke volume variation fluid therapy on lactate levels during major abdominal surgery. Hence investigators created two groups: in the intervention group fluids are given in fluid-responders (SVV > 13%) based on high value of dynamic elastance (ie. Eadyn > 0.9). In the standard group fluids are administered when SVV > 13%.

NCT ID: NCT04423224 Recruiting - Clinical trials for Haemodynamic Instability

Non-invasive Stroke Volume-based fluid Management in Elderly Patients Undergoing Hip Fracture Surgery Under Spinal Anaesthesia

AttikonHSV
Start date: January 15, 2018
Phase: N/A
Study type: Interventional

The study is going to be a single-centre prospective randomized trial. Patients will be randomly allocated to either control group (anesthetist-directed fluid therapy) or goal directed fluid therapy group, in which fluid therapy was guided by stoke volume (SV) algorithm with the use of Nexfin monitor. Primary outcome measures were the time to hospital discharge since surgery and the occurence of complications developed during the postoperative period. Secondary outcomes included the incidence of intraoperative hypotensive episodes (with MAP<65mmHg) in both groups and the requirement of vasoactive drugs to support blood pressure

NCT ID: NCT04265014 Withdrawn - Clinical trials for Hemodynamic Monitoring

Comparison of Goal-directed and Liberal Fluid Management

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

Background: The investigators aim is to indicate that the "goal directed fluid management" is more effective for open abdominal surgeries by performing perioperative hemodynamic monitorisation using a minimal invasive pulse counter analysis method. Methods: The study will be included 90 participants with ASA II-III risk score aged from 18-64 years. The prospective and randomized participants will be divided into 2 groups as liberal (Group L) and goal-directed fluid therapy (Group G) fluid treatment. Hemodynamic parameters and arterial blood gas analysis will be recorded at 30 min intervals. Preoperative and postoperative creatinine values, CR-POSSUM physiological score, Charlson comorbidity index (CCI), perioperative and postoperative vasopressor use, postoperative acute kidney injury network (AKIN), postoperative intensive care requirements, duration of hospital stay and 30-day mortality will be recorded.

NCT ID: NCT04219150 Completed - ARDS Clinical Trials

Cardiometry Versus Fluid and Catheter Treatment Trial (FACTT Lite) on Fluid Management in Acute Respiratory Distress Syndrome Patients

Start date: January 10, 2020
Phase: N/A
Study type: Interventional

The aim of this study will be to compare the fluid management in acute respiratory distress syndrome ARDS guided by electrical cardiometry (EC) versus the guidance with simplified conservative fluid protocol, Fluid and Catheter Treatment Trial "FACTT Lite". Group (A) consists of 35 patients: Fluid management in this group will follow a simplified conservative fluid protocol, "FACTT Lite" The FACTT Lite provided three possible instructions determined by the CVP and urine output: furosemide administration, fluid bolus, or no intervention. Group (B) consists of 35 patients: Fluid will be allowed according to an FTc-based fluids algorithm protocol and the type of bolus fluids will be determined according to Transthoracic fluid content (TFC), vasopressors and inotropes will be given according to reading of EC reading of systemic vascular resistance (SVR) and index of contractility (I CON).

NCT ID: NCT03208023 Terminated - Clinical trials for Fluid Responsiveness

RESIPI for Reducing Perioperative Major Adverse Cardiac Events

RESIPI
Start date: October 9, 2017
Phase: N/A
Study type: Interventional

This study aims to evaluate the effect of a novel hemodynamic management and monitoring strategy for reducing cardiac bio marker elevations and major adverse cardiac events.

NCT ID: NCT02271841 Completed - Fluid Management Clinical Trials

How Are Changing the Practices After the Introduction of the Pleth Variability Index? A Before/After Survey.

Start date: October 2014
Phase:
Study type: Observational

This study evaluated the practice before and after the introduction of a particular model pulsoxymeter giving, in addition, information on the state of fluid responsiveness of the patient.

NCT ID: NCT01602978 Completed - Anemia Clinical Trials

Comparison of Pulse Hemoglobin and Pleth Variability Index

Pleth
Start date: February 2010
Phase:
Study type: Observational

The purpose of this study is to investigate whether a validated sensor that is able to measure how much oxygen-carrying molecules called hemoglobin using pulse hemoglobin and Pleth Variability Index (PVI)] are in your blood during surgery can help your doctors manage how much fluid and possibly blood you need to get during your surgery. The hope of the study is that the device may provide an early indication you are having bleeding and this may mean you need to be treated with a transfusion. Our current method of checking this is by getting a blood sample for analysis. The investigators hope is that this device may be able to alert the clinician of the need for blood or fluids without a blood draw being needed.

NCT ID: NCT00816153 Completed - Fluid Management Clinical Trials

Pleth Variability Index and Fluid Management During Surgery

Start date: March 2008
Phase: N/A
Study type: Interventional

Pleth Variability Index (PVI) seems to be an ideal parameter to guide fluid management: dynamic parameter and non-invasive. PVI could guide fluid management during surgery and optimization of the plethysmographic-derived parameter could improve hemodynamics of the patients.