Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging

Flaccid Muscle Tone Clinical Trial

— S48  

Official title:

Mapping Human Muscle Satellite Cell Fate By Real-Time

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02685319
• Other study ID #: 1512016862
• Status: Completed
• Phase: N/A
• First received: February 10, 2016
• Last updated: June 19, 2017
• Start date: February 2016
• Est. completion date: June 2016

Study information

• Verified date: June 2017
• Source: Purdue University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging

Description:

The aim of this study is to obtain human muscle samples for cell culturing to analyze muscle cell development in real-time to uncover factors that influence growth.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 7
• Est. completion date: June 2016
• Est. primary completion date: May 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 20 Years to 29 Years

Eligibility

-Inclusion Criteria:

• men 20-29 yrs

• BMI between 20 and 34.9

• Fasting Glucose <110 mg/dL

• Blood Pressure <160/100mm Hg

• Non-Diabetic

• LDL-Cholesterol <160mg/dL

• Triacylglycerol <400 mg/dL

• Makers of kidney, liver, and heart functions within 10% of clinical normalcy

• <1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months

Exclusion Criteria:

• men <20or>29 yrs

• BMI between <20 and >34.9

• Fasting Glucose >110 mg/dL

• Blood Pressure >160/100mm Hg

• Non-Diabetic

• LDL-Cholesterol >160mg/dL

• Triacylglycerol >400 mg/dL

• Pre-existing kidney or liver conditions

-->1.5hr /wk of habitual aerobic exercise training and no resistance exercise training in the past 6 months

• Currently taking prescribed blood thinners

Related Conditions & MeSH terms

• Flaccid Muscle Tone
• Muscle Hypotonia

Intervention

Procedure:
• muscle biopsy
a muscle sample will be taken from the mid-thigh (Vastus Lateralis) and analyzed

Locations

Country	Name	City	State
United States	Purdue University - Stone Hall 700 W State St	West Lafayette	Indiana

Sponsors (1)

Lead Sponsor	Collaborator
Purdue University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging	this study is to obtain human muscle samples for cell culturing which will be exposed to a novel real-time imaging technique in order to elucidate factors that influence muscle satellite cell growth.	<10 hrs