Reducing the Duration of Untreated Psychosis

First Episode Psychosis Clinical Trial

— ReduceDUP  

Official title:

Reducing the Duration of Untreated Psychosis Through Community Education

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03102151
• Other study ID #: USCLaCLAVE
• Secondary ID: 1R01MH103830
• Status: Completed
• Start date: May 2014
• Est. completion date: August 30, 2019

Study information

• Verified date: January 2023
• Source: University of Southern California
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The study examines the possible effect of a community campaign to decrease the duration of untreated psychosis in persons with their first episode of a psychotic disorder.

Description:

The study examines whether a community campaign can reduce over time the duration of untreated psychosis (DUP) among persons with first episode psychosis (FEP). The DUP of mental health patients with FEP who sought services at a public outpatient or an inpatient facility was assessed for a 15 month period prior to the campaign launch. This serves as the baseline or historical control. The DUP will continue to be assessed for another 3 years. The hypothesis being tested is that there will be a significant decrease in DUP between baseline, one-year, two-year and three-year follow-ups. This study is being carried out with Latinos in Los Angeles County because as a group, particularly among Spanish-speaking immigrants, Latinos are at high risk for prolonged DUP.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 137
• Est. completion date: August 30, 2019
• Est. primary completion date: December 31, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 15 Years to 65 Years

Eligibility

Inclusion Criteria:

• Meet Diagnostic and Statistical Manual-4 criteria for a psychotic disorder

• of Latino origin

Exclusion Criteria:

• has a neurological disorder or suffers from brain trauma

Related Conditions & MeSH terms

• First Episode Psychosis
• Mental Disorders
• Psychotic Disorders

Intervention

Other:
• Community Campaign La CLAVE
A community campaign to teach community residents and professional networks the signs and symptoms of psychosis using social media, community talks, and advertising.

Locations

Country	Name	City	State
United States	San Fernando Mental Health Center	Granada Hills	California

Sponsors (3)

Lead Sponsor	Collaborator
University of Southern California	National Institute of Mental Health (NIMH), University of California, Los Angeles

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Latency to Treatment (LTT) a novel interview based assessment tool to measure the Duration of Untreated Psychosis	The time from the onset of psychosis to the time the subject receives appropriate mental health treatment. The metric is number of weeks that the person went without treatment from illness onset. The number of weeks is the variable of interest that will be aggregated.	At the time of recruitment into the study
Secondary	Psychosis literacy, a questionnaire based inquiry for which the respondents answer either open-ended questions (e.g., What is serious mental Illness?) or "Yes-no" questions ("e.g., Can you recognize a serious mental illness in others?)	The responses to the interview are either written down or audio-recorded. Raters then listen or read the responses and code them. The responses are aggregated as frequencies (e.g., the number of symptoms identified) or as percentages (e.g., the proportion of respondents who reported that they can recognize a serious mental illness in others).	At the time of recruitment in to study